Synfacts 2007(11): 1181-1181  
DOI: 10.1055/s-2007-991270
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Enantioselective Rhodium-Catalyzed Synthesis of N-Arylsuccinimides

Contributor(s): Hisashi Yamamoto, Marina Naodovic
W.-L. Duan, Y. Imazaki, R. Shintani*, T. Hayashi*
Kyoto University, Japan
Further Information

Publication History

Publication Date:
23 October 2007 (online)

Significance

This is an example of a very efficient synthesis of chiral N-arylsuccinimides with high diastereo- and enantioselectivity. Authors have shown that their catalytic system is applicable to other groups of compounds (ferrocobenzoqui­nones) with the same efficiency. The usefulness of the chiral succinimides obtained is described by several examples of highly stereoselective transformation.