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Synfacts 2008(1): 0060-0060
DOI: 10.1055/s-2007-991429
DOI: 10.1055/s-2007-991429
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New YorkCu(II)-Catalyzed Intramolecular Amination of Terminal Alkenes
W. Zeng, S. R. Chemler*
The State University of New York, Buffalo, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
18. Dezember 2007 (online)

Significance
This is one of the first reports on enantioselective intramolecular Cu-catalyzed carboamination of olefins. The main significance of this methodology is that it provides easy access to enantiomerically enriched sultams and sulfonamides, which have key features of many biologically active molecules.