Echovirus Type 22 Outbreak Associated with Gastro-Intestinal Disease in a Neonatal Intensive Care Unit

Emanuel Birenbaum; Rachel Handsher; Jacob Kuint; Ron Dagan; Brian Raichman; Ella Mendelson; Nehama Linder

doi:10.1055/s-2007-994182

American Journal of Perinatology, Inhaltsverzeichnis

Am J Perinatol 1997; 14(8): 469-473
DOI: 10.1055/s-2007-994182

ORIGINAL ARTICLE

Echovirus Type 22 Outbreak Associated with Gastro-Intestinal Disease in a Neonatal Intensive Care Unit

Emanuel Birenbaum¹ , Rachel Handsher² , Jacob Kuint¹ , Ron Dagan³ , Brian Raichman¹ , Ella Mendelson² , Nehama Linder¹

¹Department of Neonatalogy, Chaim Sheba Medical Center, Tel-Hashomer and the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
²The Central Virology Laboratory, Chaim Sheba Medical Center, Tel-Hashomer, Tel-Hashomer, Israel
³Pediatric Infectious Disease Unit, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel

Abstract

ABSTRACT

An echovirus type 22 outbreak involving 19 neonatal intensive care unit (NICU) patients during the months of October and November 1992 is reported. Twelve infants presented with diarrhea, 7 of whom had bloody stools and x-ray findings compatible with early stages of necrotizing enterocolitis, while one infant demonstrated characteristic pneumatosis intestinalis. Outbreaks of echovirus type 22 infection in premature infants have rarely been reported. The possibility of Echovirus 22 infection should be considered in neonatal gastrointestinal disease associated with features of necrotizing enterocolitis.

Keywords

Echovirus 22 - outbreak - neonatal - ICU

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