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Am J Perinatol 1994; 11(2): 157-159
DOI: 10.1055/s-2007-994578
ORIGINAL ARTICLE

© 1994 by Thieme Medical Publishers, Inc.

Prenatal Sonographic Evidence Supporting an in Utero Developmental Etiology of Möbius Sequence

David M. Sherer, Patrick Spafford
  • The Division of Maternal-Fetal Medicine, The Department of Obstetrics and Gynecology, and The Division of Neonatology, The Department of Pediatrics, Strong Memorial Hospital, The University of Rochester School of Medicine & Dentistry, Rochester, New York
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Publication History

Publication Date:
04 March 2008 (online)

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ABSTRACT

Mobius sequence features masklike facies with sixth and seventh nerve palsy and frequently micrognathia thought to result from a neuromuscular deficiency in early movement of the mandible. Failure to thrive in infancy is commonly due to feeding and aspiration difficulties. We present the first description of prenatal sonographic findings associated with this lesion, which also support an in utero developmental etiology of this rare condition.