Synfacts 2008(4): 0403-0403  
DOI: 10.1055/s-2008-1042816
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York

Gold-Catalyzed Oxidative Coupling

Contributor(s): Paul Knochel, Tobias Thaler
A. Kar, N. Mangu, H. M. Kaiser, M. Beller, M. K. Tse*
Leibniz-Institut für Katalyse e.V. an der Universität Rostock and Universität Rostock, Germany
Further Information

Publication History

Publication Date:
19 March 2008 (online)


Gold-catalyzed oxidative homocoupling with simple arenes was realized for the first time. C-H functionalization was shown to proceed with remarkable functional group tolerance, where even iodo-substituents were tolerated. For this coupling reaction no inert atmosphere or pretreatment of the solvent was required. The reaction could simply be performed in air without the exclusion of moisture.