Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2008(5): 0470-0470
DOI: 10.1055/s-2008-1072547
DOI: 10.1055/s-2008-1072547
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart · New York
A [2+2] Approach to Unsymmetrical Chlorins
W. G. O’Neal, P. A. Jacobi*
Dartmouth College, Hanover, USA
Further Information
Publication History
Publication Date:
23 April 2008 (online)
Significance
Chlorins are a family of natural chromophores that can be found in many terrestrial and marine organisms, the most notable member being chlorophyll a. Additionally, synthetic variants have found application in materials science, light-energy conversion, and photodynamic therapy for the treatment of certain cancers. Controlling the nature and position of substituents around the chlorin nucleus is critical for tuning of their properties. The authors present several strategies to obtain unsymmetrical chlorins, two of which are shown above.