1,2-Rearrangement of α,α-Disubstituted α-Siloxy Aldehydes: Switchable Regioselectivity

Significance

The regioselectivity of the 1,2-rearrangement reaction in α,α-disubstituted α-siloxy aldehydes can be switched either in favor of the transfer of the aryl or alkyl moiety depending on the nature of the Al catalyst and the respective conditions. In both cases the reactions proceed with good to excellent regioselectivities.