Plasmablastic lymphoma (PBL) is a rare type of non-Hodgkin lymphoma frequently related
to HIV infection. We report a case of PBL in a 7 year old female child with transfusion-acquired
HIV infection on antiretroviral therapy (ART). The presentation was a swelling in
the skull and cervical lymphadenopathy. CT scan revealed bony erosions with meningeal
enhancement. The patient was started on chemotherapy and cranial irradiation but succumbed
to death in 5 months. This is the first reported case of PBL involving the skull and
meninges in a HIV-infected child.
Keywords
HIV - Plasmablastic lymphoma - skull
