Journal of Pediatric Epilepsy 2012; 01(03): 143-149
DOI: 10.3233/PEP-2012-024
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Benign familial neonatal epilepsy

Courtney J. Wusthoff
a   Division of Neonatology, Hammersmith Hospital, London, UK
› Author Affiliations

Subject Editor:
Further Information

Publication History

21 November 2011

22 February 2012

Publication Date:
17 July 2015 (online)


Benign familial neonatal epilepsy (BFNE), previously benign familial neonatal seizures, is a relatively rare epilepsy syndrome arising in newborns. The genetic basis for this syndrome has recently been defined. This review uses a case to illustrate the challenges in the clinical approach to diagnosis in neonatal epilepsy, and gives the clinician a summary of the genetic basis for BFNE. Finally, an overview of counseling and clinical treatment of BFNE is discussed.