J Pediatr Intensive Care 2014; 03(04): 291-304
DOI: 10.3233/PIC-14111
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Parasitic disease in the pediatric intensive care unit - A review of severe manifestations of pediatric parasitic disease

Juan D. Chaparro
a   Department of Pediatrics, Division of Infectious Diseases, University of California San Diego, San Diego, CA, USA
John A.D. Leake
b   Quest Diagnostics, San Juan Capistrano, CA, USA
› Author Affiliations

Subject Editor:
Further Information

Publication History

20 October 2014

02 December 2014

Publication Date:
28 July 2015 (online)


Parasitic diseases, previously thought to be the domain of developing nations only, are being increasingly recognized as a significant source of morbidity/mortality in developed and developing nations alike. While many parasites cause long-term low-level disease, some parasitic diseases can have severe manifestations necessitating intensive care unit admission. In this review, we focus on severe malaria (including cerebral malaria), neurocysticercosis, Strongyloides hyperinfection syndrome, American trypanosomiasis (Chagas disease), baylisascariasis and amoebic meningoencephalitis.