Multiple Sklerose – Einfluss der Ernährung und des Darmmikrobioms

Zusammenfassung

Multiple Sklerose (auch Encephalomyelitis disseminata, ED) ist die häufigste chronisch entzündliche Autoimmunerkrankung des zentralen Nervensystems (ZNS). Die Ursachen der Autoimmunerkrankung sind bis heute nicht vollständig geklärt. Die Wissenschaft vermutet jedoch zwischenzeitlich, dass genetische Faktoren nur eine untergeordnete Rolle spielen. Die stetige Zunahme der Diagnoseprävalenz der Multiplen Sklerose in den letzten 30 Jahren wird v. a. in Verbindung gebracht mit einer Dysregulation des Immunsystems durch anthropogene Umweltveränderungen. Industriekost, die reich an gesättigten tierischen Fetten und raffinierten Kohlenhydraten ist, begünstigt die Entwicklung von entzündlichen Erkrankungen. Unsere Ernährung beeinflusst über die Mikroorganismen im Darm die Immunzellen des Gehirns und damit auch den Verlauf von MS.

Abstract

Multiple sclerosis (also called encephalomyelitis disseminata, ED) is the most common chronic inflammatory autoimmune disease of the central nervous system (CNS). The causes of the autoimmune disease are still not fully established. However, scientists now suspect that genetic factors only play a subordinate role. The steady increase of the diagnostic prevalence of multiple sclerosis during the last 30 years has been primarily associated with a dysregulation of the immune system due to anthropogenic environmental changes. Industrial food, which is rich in saturated animal fats and refined carbohydrates, encourages the development of inflammatory diseases. Our nutrition influences the immune cells of the brain via the microorganisms in the intestine and thus also the course of MS.

Schlüsselwörter

Multiple Sklerose - Ernährung - Autoimmunität - Darmmikrobiom - Umweltfaktoren

Key words

Multiple sclerosis - nutrition - autoimmunity - intestinal microbiome - environmental factors

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