Weak Coordination-Assisted Cobalt(III)-Catalyzed Regioselective Alkenylation of Indolines with Allenes

Dedication

On the occasion of Prof. S. Chandrasekaran’s 80th birthday.

Abstract

A cobalt(III)-catalyzed regioselective coupling of indolines with allenes is reported to access C7-alkenyl indolines in good to high yields. The method features weakly coordinating-group assistance, broad functional-group tolerance, including pharmacophores, scalability, and a reversible C–H activation step.

Keywords

Cobalt - Allenes - Indolines - C–H alkenylation

Publication History

Received: 29 September 2025

Accepted after revision: 17 October 2025

Accepted Manuscript online:
17 October 2025

Article published online:
26 November 2025

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