Synfacts, Table of Contents Synfacts 2026; 22(01): 12DOI: 10.1055/a-2739-0565 Synthesis of Heterocycles Modular Hoffman–Löffler–Freytag Approach to Azacyclic Systems Authors Contributor(s): Paul Richardson (Pfizer) Recommend Article Abstract Buy Article(opens in new window)Keywords KeywordsC–H amination - pyrrolidines - bridged bicycles - spirocycles - fused azacycles - Hoffman–Löffler–Freytag (HLF) mechanism Full Text