Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2008(12): 1339-1339
DOI: 10.1055/s-0028-1083554
DOI: 10.1055/s-0028-1083554
Polymer-Supported Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
A Bimetallic, Heterogeneous, Multifunctional Catalyst
Contributor(s):Yasuhiro Uozumi, Yoichi M. A. YamadaB. H. Lipshutz*, D. M. Nihan, E. Vinogradova, B. R. Taft, Z. V. Bokovi
University of California, Santa Barbara, USA
Copper + Nickel-in-Charcoal (Cu-Ni/C): A Bimetallic, Heterogeneous Catalyst for Cross-Couplings
Org. Lett. 2008, 10: 4279-4282
University of California, Santa Barbara, USA
Copper + Nickel-in-Charcoal (Cu-Ni/C): A Bimetallic, Heterogeneous Catalyst for Cross-Couplings
Org. Lett. 2008, 10: 4279-4282
Further Information
Publication History
Publication Date:
20 November 2008 (online)
Key words
multifunctional catalysts - cross-coupling - nickel - copper - charcoal
Significance
A bimetallic heterogeneous catalyst, 2Cu-8Ni/C, of copper and nickel oxide particles in charcoal was prepared. The resulting catalyst promoted a variety of cross-couplings typically associated with group 10 and 11 transition metal catalysts. The catalyst was reused once without loss of catalytic activity.
Comment
More than one metal are housed in the solid support, and hence, the resulting catalyst mediates multiple types of bond constructions. A tandem click reaction-amination of 19 was carried out with the multifunctional catalyst to give the coupling product 20 in 54%.