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Synfacts 2009(8): 0863-0863  
DOI: 10.1055/s-0029-1217446
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Diastereo- and Regioselective Silacyclopropanation of Allenes

Contributor(s): Mark Lautens, Jane Panteleev
K. M. Buchner, T. B. Clark, J. M. N. Loy, T. X. Nguyen, K. A. Woerpel*
University of California, Irvine, USA
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Publication History

Publication Date:
23 July 2009 (online)

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Significance

This article reports the metal-mediated silylene transfer to allenes yielding silacyclopropanes 2, and builds on the group’s earlier work with silacyclopropanations (J. Am. Chem. Soc. 2004, 126, 9522). The marked utility of such reactive compounds is demonstrated by their insertion with aldehydes.