Endoscopy 2010; 42(2): 98-103
DOI: 10.1055/s-0029-1243839
Original article

© Georg Thieme Verlag KG Stuttgart · New York

Value of high-frequency miniprobes and conventional radial endoscopic ultrasound in the staging of early Barrett's carcinoma

O.  Pech1 , E.  Günter1 , F.  Dusemund1 , C.  Ell1
  • 1Department of Internal Medicine, HSK Wiesbaden, Wiesbaden, Germany
Further Information

Publication History

submitted 4 May 2009

accepted after revision 18 October 2009

Publication Date:
05 February 2010 (online)

Background and aims: High-frequency miniprobes (HFPs) and conventional radial endoscopic ultrasonography (crEUS) are considered valuable tools in the staging of early Barrett's cancer. However, there is some controversy on whether HFPs are superior in the T staging of Barrett's cancer or whether the same level of accuracy can be achieved by the sole use of crEUS.

Patients and methods: Patients referred for endoscopic treatment for Barrett's cancer were included in this prospective crossover trial and were randomly assigned to either HFPs or crEUS as the initial diagnostic method. Afterwards, all of the patients were re-examined with the alternative procedure. The staging results obtained with each method were documented prospectively.

Results: A total of 43 patients (median age 66 years [interquartile range: 58 – 73]; 34-male) were included. A total of 23 mucosal and 16 submucosal Barrett's cancers were confirmed at histology. Histological confirmation was not possible in four patients. Assessment of the T category was not possible with HFPs in 7 % of patients, compared with 33 % with crEUS (P < 0.0001) due to positioning problems. T category was correctly assessed with HFP in 64 % of patients and with crEUS in 49 %.

Conclusions: HFPs are significantly superior to crEUS for local staging of Barrett's cancer. However, the accuracy of assessment of the T category was unsatisfactory with both techniques.

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O. PechMD, PhD 

Department of Internal Medicine 2
HSK Wiesbaden

Ludwig-Erhard-Strasse 100
65199 Wiesbaden
Germany

Fax: +49-611-432418

Email: oliver.pech@t-online.de

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