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DOI: 10.1055/s-0029-1245647
© Georg Thieme Verlag KG Stuttgart · New York
Topische Anästhesie in der Kataraktchirurgie
Topical Anaesthesia in Cataract SurgeryPublication History
Eingegangen: 29.4.2010
Angenommen: 30.7.2010
Publication Date:
12 August 2010 (online)

Zusammenfassung
Mit der Etablierung der modernen Kataraktchirurgie als Operation in einem geschlossenen System wurde die topische Anästhesie eingeführt. Die alleinige Tropfanästhesie ermöglicht zwar eine gute Analgesie in den meisten Fällen. Bis zu 30 % der Patienten fühlen sich jedoch während der einzelnen Operationsschritte unwohl und berichten von Schmerzen, die gerade noch erträglich sind. Die Oberflächenanästhesie kann durch Modifikation der Applikationsformen wie Schwämmchen, Gel oder mit der subkonjunktivalen Anästhesie intensiviert werden. Mit der Einführung der intrakameralen Anästhesie in den 90er-Jahren, vor allem mit unkonserviertem Lidocain 1 %, wurde die Effektivität der topischen Anästhesie signifikant verbessert, sodass diese kombinierte Anästhesie als Routineverfahren angewendet werden kann. Eine anästhesiologische Prämedikation und Überwachung ist eine sinnvolle Ergänzung der lokalen Anästhesie, da die meisten Kataraktpatienten häufig im hohen Alter sind und kardiovaskuläre Erkrankungen haben. An knapp 10 % der operierten Patienten können Beeinträchtigungen der kardiopulmonalen Parameter festgestellt werden. In ca. 2,6 % ist eine anästhesiologische Intervention notwendig.
Abstract
Topical anaesthesia was introduced together with the establishment of modern cataract surgery as an operation in a closed system. Superficial anaesthesia by itself leads to a good analgesia in most cases. However, up to 30 % of the patients feel uncomfortable or even experience pain during surgery. Superficial anaesthesia can be intensified with subconjunctival infiltration or by modifying the application forms such as sponges or gel. With the introduction of the intracameral anaesthesia in the 1990 s primarily with unpreserved lidocaine 1 %, the efficacy of the topical anaesthesia was improved significantly. The combined topical anaesthesia plus intracameral lidocaine administration can be used as a routine method. A general anaesthesia care for premedication and monitoring during cataract surgery is useful since most cataract patients are of advanced age and frequently suffer from cardiovascular diseases. In almost 10 % of the patients changes in cardiopulmonal comorbidities were observed and in 2.6 % anaesthesia intervention was required.
Schlüsselwörter
Kataraktchirurgie - topische Anästhesie - intrakamerale Anästhesie - Sedierung - Lidocain
Key words
cataract surgery - topical anaesthesia - intracameral anaesthesia - sedation - lidocaine
Literatur
- 1
Amiel H, Koch P S.
Tetracaine hydrochloride 0,5 % versus lidocaine 2 % jelly as a topical anesthetic
agent in cataract surgery: comparative clinical trial.
J Cataract Refract Surg.
2007;
33 (1)
98-100
Reference Ris Wihthout Link
- 2
Assia E l, Pras E, Yehezkel M et al.
Topical anesthesia using lidocaine gel for cataract surgery.
J Cataract Refract Surg.
1999;
25
635-639
Reference Ris Wihthout Link
- 3 Auffarth G U, Borkenstein A FM, Limberger I J. et al .Prospektive Safety-Studie zum Viskoelastikum Visthesia. In: Auffarth, (Hrsg.) 22. Kongreß der Deutschen Gesellschaft für Intraokularlinsen Implantation. Berlin, Heidelberg; 2008: 43-47
Reference Ris Wihthout Link
- 4
Behnig A, Linden C.
Aeqous humor lidocaine concentrations in topical and intracameral anaesthesia.
J Cataract Refract Surg.
1998;
24
1598-1601
Reference Ris Wihthout Link
- 5
Belluci R, Morselli S, Pucci V et al.
Intraocular penetration of topical lidocain 4 %.
J Cataract Refract Surg.
1999;
25
643-647
Reference Ris Wihthout Link
- 6
Bhananker S M, Posner K L, Cheney F W et al.
Injury and liability associated with monitored anesthesia care: A closed claim analysis.
Anesthesiology.
2006;
104
228-234
Reference Ris Wihthout Link
- 7
Biró Z, Schvöller M.
Subjective visual sensations during cataract surgery performed under topical anaesthesia.
Acta Ophthalmol.
2008;
86 (8)
894-896
Reference Ris Wihthout Link
- 8
Bloomberg L B, Pellkan K J.
Topical anaesthesia using the Bloomberg super Numb Anesthetic Ring.
J Cataract Refract Surg.
1995;
21
16-20
Reference Ris Wihthout Link
- 9
Boezaart A, Berry R A, Nell M.
Topical anesthesia versus retrobulbar block for cataract surgery: the patient’s perspective.
J Clin Anesth.
2000;
12
58-60
Reference Ris Wihthout Link
- 10
Bouillon T, Garstka G, Stafforst D et al.
Piritramide and alfentanil display similar respiratory depressant potency.
Acta Anaesthesiol Scand.
2003;
47 (10)
1231-1241
Reference Ris Wihthout Link
- 11
Dick B, Jacobi F K.
Kataraktchirurgie und Antikoagulation – derzeitiger Stand.
Klin Monatsbl Augenheilkd.
1996;
209 (12)
340-346
Reference Ris Wihthout Link
- 12
Chang Y S, Tseng S Y, Tseng S H et al.
Cytotoxicity of lidocaine or bupivacaine on corneal endothelial cells in a rabbit
model.
Cornea.
2006;
25 (5)
590-596
Reference Ris Wihthout Link
- 13
Davis D B, Mandel M R.
Posterior peribulbar anesthesia: An alternative to retrobulbar anesthesia.
J Cataract Refract Surg.
1986;
12
182-184
Reference Ris Wihthout Link
- 14
Davis D B, Mandel M R.
Efficacy and complication rate of 16 224 consecutive peribulbar blocks, a prospective
multicenter study.
J Cataract Refract Surg.
1994;
20
327-337
Reference Ris Wihthout Link
- 15 Dolder R. Pharmakologie, Biopharmazie und Galenik der Augenarzneimittel. Ophthalmika. Wissenschaftliche Verlagsgesellschaft mbH. Stuttgart; 1983: 73-80
Reference Ris Wihthout Link
- 16
Eke T, Thompson J R.
Serious complications of local anaesthesia for cataract surgery: a 1 year national
survey in the United Kingdom.
Br J Ophthalmol.
2007;
91 (4)
470-475
Reference Ris Wihthout Link
- 17
Elvira J C, Hueso J R, Marinez-toldos J et al.
Induced endothelial cell loss in phacoemulsification using topical anesthesia plus
intracameral lidocaine.
J Cataract Refract Surg.
1999;
25 (5)
640-642
Reference Ris Wihthout Link
- 18
Erdurmus M, Aydin B, Usta B et al.
Patient comfort and surgeon satisfaction during cataract surgery using topical anesthesia
with or without dexmedetomidine sedation.
Eur J Ophthalmol.
2008;
18 (3)
361-367
Reference Ris Wihthout Link
- 19
Ezra D G, Nambiar A, Allan B D.
Supplementary intracameral lidocaine for phacoemulsification under topical anesthesia.
A meta-analysis of randomized controlled trials.
Ophthalmology.
2008;
115 (3)
455-487
Reference Ris Wihthout Link
- 20 Fine I H, Fichman R A, Grabow H R. Clear-corneal cataract surgery and topical anesthesia. Slack Inc. New York; 1993 1. Auflage
Reference Ris Wihthout Link
- 21
Fung D, Cohen M M, Stewart S et al.
What determines patient satisfaction with cataract care under topical local anesthesia
and monitored sedation in a community hospital setting?.
Anesth Analg.
2005;
100
1644-1650
Reference Ris Wihthout Link
- 22
Gan T J et al.
Society for Ambulatory Anesthesia Guidelines for the Management of Postoperative Nausea
and Vomiting.
Anesth Analg.
2007;
105
1615-1628
Reference Ris Wihthout Link
- 23
Gills J, Cherchio M, Raanan M G.
Unpreserved lidocaine to control discomfort during cataract surgery using topical
anesthesia.
J Cataract Refract Surg.
1997;
23
545-550
Reference Ris Wihthout Link
- 24
Gills J P.
Corneal endothelial toxicity of topical anesthesia.
Ophthalmology.
1998;
105 (7)
1126-1127
Reference Ris Wihthout Link
- 25
Harman D M.
Combined sedation and topical anesthesia for cataract surgery.
J Cataract Refract Surg.
2000;
26 (1)
109-113
Reference Ris Wihthout Link
- 26
Heuermann T, Hartmann C, Anders N.
Long-term endothelial cell loss after phacoemulsification: peribulbar anesthesia versus
intracameral lidocaine 1 %: prospective randomized clinical trial.
J Cataract Refract Surg.
2002;
28 (4)
639-643
Reference Ris Wihthout Link
- 27 Heuermann T, Anders N, Rüther K. et al .Retinale Funktion nach intraokularer Lidocaingabe bei der Kataraktoperation. In Duncker G, (Hrsg.) 12. Kongreß der Deutschen Gesellschaft für Intraokularlinsen Implantation. Berlin, Heidelberg; 1999: 348-351
Reference Ris Wihthout Link
- 28
Hoffmann R S, Fine H.
Transient no light perception visual acuity after intracameral lidocaine injection.
J Cataract Surg.
1997;
23
957-958
Reference Ris Wihthout Link
- 29
Holas A, Kraft P, Marcovic M et al.
Remifentanil, propofol or both for conscious sedation during eye surgery under regional
anesthesia.
Eur J Anaesthesiol.
1999;
16
741-748
Reference Ris Wihthout Link
- 30
Irle S, Lückefahr M H, Tomalla M.
Topische Anästhesie als Routineverfahren bei der Kataraktchirurgie – Schmerzbewertung
und Komplikation bei einem größeren Patientenkollektiv.
Klin Monatsbl Augenheilkd.
2005;
222 (1)
36-40
Reference Ris Wihthout Link
- 31
Johansson M, Lundberg B, Behndig A.
Optical coherence tomography evaluation of macular edema after phacoemulsification
surgery with intracameral mydriatics.
J Cataract Refract Surg.
2007;
33 (8)
1436-1441
Reference Ris Wihthout Link
- 32
Kim T, Holley G P, Lee J H et al.
The effects of intraocular lidocaine on the corneal endothelium.
Ophthalmology.
1998;
105 (1)
125-130
Reference Ris Wihthout Link
- 33
Koch P S.
Efficacy of lidocaine 2 % jelly as a topical agent in cataract surgery.
J Cataract Refract Surg.
1999;
25
632-634
Reference Ris Wihthout Link
- 34
Koch P S.
Anterior chamber irrigation with unpreserved lidocaine 1 % for anesthesia during cataract
surgery.
J Cataract Refract Surg.
1997;
23
551-554
Reference Ris Wihthout Link
- 35
Kohnen T.
Editor: Is intracamral anesthetic application the final solution to topical anesthesia
for cataract surgery.
J Cataract Refract Surg.
1999;
25
601-602
Reference Ris Wihthout Link
- 36 Koller C. Vorläufige Mitteilung über locale Anästhesierung am Auge. Vortrag (verlesen von J
Brettauer) auf der 16. Versammlung der Ophthalmologischen Gesellschaft, Heidelberg,
15. September 1884. Heidelberg, Rostock: Der Vers Ophthalmol Gesellschaft;
Reference Ris Wihthout Link
- 37
Koopmans S A, Rij van G.
Cataract surgery and anticoagulants.
Doc Ophthalmol.
1996 – 1997;
92 (1)
11-6
Reference Ris Wihthout Link
- 38
Kumar N, Rowbotham D J.
Editorial II Piritramide.
British Journal of Anesthesia.
1999;
82 (1)
3-5
Reference Ris Wihthout Link
- 39
Laude A, Au Eong K G, Mills K B.
Knowledge of visual experience during cataract surgery under local anaesthesia: a
nationwide survey of UK ophthalmologists.
Br J Ophthalmol.
2009;
93 (4)
510-512
Reference Ris Wihthout Link
- 40
Leaming D V.
Practice styles and preferences of ASCRS members 1993.
J Cataract Refract Surg.
1994;
20
459
Reference Ris Wihthout Link
- 41 Leaming D. MDs surveys. Zitiert n. ES Rosen
Reference Ris Wihthout Link
- 42
Masket S, Gokmen F.
Efficacy and safety of intracameral lidocaine as a supplement to topical anesthesia.
J Cataract Refract Surg.
1998;
24
956-960
Reference Ris Wihthout Link
- 43
Oei-Lim V L, Dijkgraaf M G, Smet M D et al.
Does cerebral monitoring improve ophthalmic surgical operating conditions during propofol-induced
sedation?.
Anesth Analg.
2006;
103
1189-1195
Reference Ris Wihthout Link
- 44
Perone J M, Popovici de A, Ouled-Moussa R et al.
Safety and efficacy of two ocular anesthetic methods for phacoemulsification: topical
anesthesia and viscoanesthesia (VisThesia).
Eur J Ophthalmol.
2007;
17 (2)
171-177
Reference Ris Wihthout Link
- 45
Pham D T, Scherer V, Wollensak J.
Sponge-Oberflächenanästhesie in der Kataraktchirurgie (bei skleralem Tunnelschnitt).
Klin Mbl Augenheilkd.
1996;
209
347-353
Reference Ris Wihthout Link
- 46 Pham D T, Weller A, Pfeiffer S. et al .Schmerzempfindlichkeit nach intrakammeraler Lidocain-Application versus Sponge-Anästhesie
in der Kataraktchirurgie. In Duncker G, (Hrsg.) 12. Kongreß der Deutschen Gesellschaft für Intraokularlinsen Implantation. Berlin, Heidelberg; 1999: 758-760
Reference Ris Wihthout Link
- 47
Poyales-Galan F, Pirazolli G.
Clinical evaluation of endothelial cell decrease with VisThesia in phacoemulsification
surgery.
J Cataract Refract Surg.
2005;
31 (11)
2157-2161
Reference Ris Wihthout Link
- 48
Reinhardt S, Burkhardt U, Nestler A et al.
Use of piritramide for analgesia and sedation during peribulbar nerve block for cataract
surgery.
Ophthalmologica.
2002;
216 (4)
256-260
Reference Ris Wihthout Link
- 49
Rosen E S.
Editor: Iatrogenic puncture wounds?.
J Cataract Refract Surg.
2010;
36
879-880
Reference Ris Wihthout Link
- 50
Sanmugasunderam S, Khalfan A.
Is fasting required before cataract surgery? A retrospective review.
Can J Opthalmol.
2009;
44 (6)
655-6
Reference Ris Wihthout Link
- 51
Schmid E, Neumayer T, Rainer G et al.
Intrakamerale Lidocainanästhesie bei Kataraktoperationen: Effektivität und Sicherheit
Applikation während der Hydrodissektion.
Spektrum der Augenheilkunde.
2008;
22 (1)
26-30
Reference Ris Wihthout Link
- 52
Schrader W F, Schargus M, Schneider E et al.
Risks and sequelae of scleral perforation during peribulbäre or retrobulbäre anesthesia.
J Cataract Refract Surg.
2010;
36
885-889
Reference Ris Wihthout Link
- 53
Sekundo W, Dick H B, Schmidt J C.
Lidocaine-assisted xylocaine jelly anesthesia versus one quadrant sub-Tenon infiltration
for self-sealing sclerocorneal incision routine phacoemulsification.
Eur J Ophthalmol.
2004;
14 (2)
111-116
Reference Ris Wihthout Link
- 54
Sharwood P L, Thomas D, Roberts T V.
Adverse medical events associated with cataract surgery performed under topical anaesthesia.
Clin Experiment Ophthalmol.
2008;
36 (9)
842-846
Reference Ris Wihthout Link
- 55
Stifter E, Menapace R.
„Instant vision” compared with postoperative patching: clinical evaluation and patient
satisfaction after bilateral cataract surgery.
Am J Ophthalmol.
2007;
143 (3)
441-448
Reference Ris Wihthout Link
- 56
Strobel J, Hühnermann M.
Tropfanästhesie in der Kataraktchirurgie.
Ophthalmologe.
1996;
93
68-72
Reference Ris Wihthout Link
- 57
Stupp T, Hassouna I, Soppart K et al.
Systemic adverse events: a comparison between topical and peribulbar anaesthesia in
cataract surgery.
Ophthalmologica.
2007;
221 (5)
320-325
Reference Ris Wihthout Link
- 58
Tseng S H, Chen F K.
A randomized clinical trial of combined topical-intracameral anesthesia in cataract
surgery.
Ophthalmology.
1998;
105 (11)
2007-2011
Reference Ris Wihthout Link
- 59
Unal M, Yücel I, Sarici A et al.
Phacoemulsification with topical anesthesia: Resident experience.
J Cataract Refract Surg.
2006;
32 (8)
1361-1365
Reference Ris Wihthout Link
- 60
Välimäki J, Törnblom R M.
Viscoanaesthesia in cataract surgery: a prospective, randomized clinical trial.
Acta Ophthalmol.
2009;
87 (4)
378-381
Reference Ris Wihthout Link
- 61 Weindler J, Rippa A, Kiefer T. et al .Niedrig dosiertes Midazolam (3,75 mg) und Clonidin (0,15 mg) zur oralen Prämedikation
bei Retrobulbäranästhesie. In Robert Y CA, (Hrsg.) 7. Kongreß der Deutschen Gesellschaft für Intraokularlinsen Implantation. Berlin, Heidelberg, New York: Springer-Verlag; 1993: 70-75
Reference Ris Wihthout Link
- 62
Weindler J, Weindler M, Ruprecht K W.
Lokalanästhesie in der Ophthalmochirurgie.
Ophthalmologe.
2004;
101
847-865
Reference Ris Wihthout Link
- 63
Weller A, Pham D T, Häberle H.
Kataraktchirurgie. Sponge-Oberflächen-Anästhesie mit intracameraler Lidocain-Applikation.
Ophthalmologe.
2000;
97 (1)
51-53
Reference Ris Wihthout Link
- 64
Weller A, Pham D T, Häberle H.
Intracameral anesthesia with lidocaine in cornea guttata.
Ophthalmologe.
2002;
99 (1)
29-31
Reference Ris Wihthout Link
- 65 Weller A. Sponge-Oberflächen- und intracamerale Anästhesie. Eine Alternative der Peri- und Retrobulbäranästhesie
in der Kataraktchirurgie. Dissertation. Freie Universität Berlin; 2001
Reference Ris Wihthout Link
- 66 Wenzel M, Pham D T, Scharrer A et al. Ergebnisse der Umfrage 2009 von BDOC, BVA und der DGII, 24. Kongreß der Deutschen
Gesellschaft für Intraokularlinsen Implantation. Biermann Verlag. (i. Druck)
Reference Ris Wihthout Link
- 67
Wirbelauer C, Iven H, Bastian C et al.
Systemic levels of lidocaine after intracameral injection during cataract surgery.
J Cataract Refract Surg.
1999;
25
648-651
Reference Ris Wihthout Link
- 68
Wirbelauer C, Weller A, Häberle H. et al.
Kataraktoperation in topischer Anästhesie unter oraler Antikoagulation.
Klin Monatsbl Augenheilkd.
2004;
221
749-752
Reference Ris Wihthout Link
- 69
Zakrzewski P A, Banashkevich A V, Friel T et al.
Monitored anesthesia care by registered respiratory therapists during cataract surgery:
an update.
Ophthalmology.
2010;
117 (5)
897-902
Reference Ris Wihthout Link
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