Pd-Catalyzed Decarboxylative Cross-Coupling to Yield Aryl
Ketones

doi:10.1055/s-0030-1260501

Subscribe to RSS

Please copy the URL and add it into your RSS Feed Reader.

https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml

Share / Bookmark

Facebook Linkedin Weibo

Download PDF

Synfacts 2011(7): 0776-0776
DOI: 10.1055/s-0030-1260501

Metal-Mediated Synthesis

Pd-Catalyzed Decarboxylative Cross-Coupling to Yield Aryl Ketones

Contributor(s): Paul Knochel, Andreas K. Steib
M. Li, C. Wang, H. Ge*
Indiana University Purdue University Indianapolis, USA

Further Information

Publication History

Publication Date:
17 June 2011 (online)

Permissions and Reprints

Significance

A novel palladium-catalyzed decarboxylative cross-coupling of potassium aryltrifluoroborates with α-oxocarboxylic acids to afford aryl ketones has been disclosed. A combination of catalytic Pd(OAc)₂ with stoichiometric K₂S₂O₈ was found to be the most efficient system for the reaction.