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Synfacts 2011(10): 1094-1094  
DOI: 10.1055/s-0030-1261058
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Catalytic Enantioselective Synthesis of Tetrahydro-4-ones

Contributor(s): Hisashi Yamamoto, Patrick Brady
M. Iqbal, N. Mistry, P. A. Clarke*
University of York, UK
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Publication History

Publication Date:
20 September 2011 (online)

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Significance

Tetrahydropyrans are of great interest due to the numerous biologically active natural products that bear this structure. The described method is very practical, creating these highly functionalized molecules with excellent control of enantioselectivity from readily available starting materials.