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Synfacts 2011(10): 1146-1146  
DOI: 10.1055/s-0030-1261094
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Hosomi-Sakurai Reaction with Silicomolybdic Acid

Contributor(s): Yasuhiro Uozumi, Yoichi M. A. Yamada, Aya Ohno
K. Murugan, S. Srimurugan, C. Chen*
National Dong Hwa University, Hualien, Taiwan
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Publication History

Publication Date:
20 September 2011 (online)

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Significance

SMA/SiO2 (SMA: silicomolybdic ­acid) was applied to the Hosomi-Sakurai allylation. The reaction of carbonyl compounds 1 with allyl­trimethylsilane and benzyl alcohol gave the corres­ponding homoallylic benzyl ethers 2 in 30-99% yield (30 examples). The reaction of acetals, ketals and acylals (3, 8 examples) with allyltrimethylsilane were also examined under similar conditions.