Mucoepidermoid Carcinoma as a Masquerade Syndrome of Scleral Melting and Granulomatous Kerato-Uveitis

Introduction

Mucoepidermoid carcinoma is a rare conjunctival tumour demonstrating locally aggressive behaviour, composed of cells with squamous differentiation and cells with mucin production. This tumour was initially described in the salivary glands, these being most frequently involved. It has also been described in the lungs and, more rarely, in the nasal mucosa. Involvement of the conjunctiva is rare with less than thirty cases reported up to date to the best of our knowledge. Intraocular invasion is not uncommon and has been documented in several cases [1] [2] [3] [4] [5] [6].

We present here an unsuspected mucoepidermoid carcinoma with intraocular extension, with an unusually long clinical presentation where the diagnosis was determined histopathologically only after evisceration.

References

• 1 Gunduz K et al. Intraocular neoplastic cyst from mucoepidermoid carcinoma of the conjunctiva.  Arch Ophthalmol. 1998;  116 1521-1523
• 2 Seitz B, Henke V. Mucoepidermoid carcinoma of the epibulbar connective tissue with diffuse intraocular epithelial invasion.  Klin Monatsbl Augenheilkd. 1995;  207 264-265
• 3 Lacour S, Legeais J M, D’Hermies F et al. Mucoepidermoid carcinoma of the conjunctiva with intraocular invasion. Apropos of a case.  J Fr Ophtalmol. 1991;  14 349-352
• 4 Searl S S, Krigstein H J, Albert D M. Invasive squamous cell carcinoma with intraocular mucoepidermoid features. Conjunctival carcinoma with intraocular invasion and diphasic morphology.  Arch Ophthalmol. 1982;  100 109-111
• 5 Brownstein S. Mucoepidermoid carcinoma of the conjunctiva with intraocular invasion.  Ophthalmology. 1981;  88 1226-1230
• 6 Rao N A, Font R L. Mucoepidermoid carcinoma of the conjunctiva: a clinicopathologic study of five cases.  Cancer. 1976;  38 1699-1709
• 7 Hwang I P, Jordan D R, Brownstein S et al. Mucoepidermoid carcinoma of the conjunctiva: a series of three cases.  Ophthalmology. 2000;  107 801-805
• 8 Biswas J, Datta M, Subramaniam N. Mucoepidermoid carcinoma of the conjunctiva of the lower lid--report of a case.  Indian J Ophthalmol. 1996;  44 231-233
• 9 Carrau R L, Stillman E, Canaan R E. Mucoepidermoid carcinoma of the conjunctiva.  Ophthal Plast Reconstr Surg. 1994;  10 163-168
• 10 Robinson J W, Brownstein S, Jordan D R et al. Conjunctival mucoepidermoid carcinoma in a patient with ocular cicatricial pemphigoid and a review of the literature.  Surv Ophthalmol. 2006;  51 513-519