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Am J Perinatol 2013; 30(09): 715-722
DOI: 10.1055/s-0032-1331027
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Obstetric and Neonatal Implications of a Low Value on the 50-g Glucose Screening Test

Kimberly K. Ma
1   Department of Obstetrics and Gynecology of the Oregon Health and Science University, Portland, Oregon
,
Lisa Mele
2   The George Washington University Biostatistics Center, Rockville, Maryland
,
Mark B. Landon
3   The Ohio State University, Columbus, Ohio
,
Catherine Y. Spong
4   The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland
,
Susan M. Ramin
5   The University of Texas Health Science Center at Houston, Houston, Texas
,
Brian Casey
6   University of Texas Southwestern Medical Center, Dallas, Texas
,
Ronald J. Wapner
7   Columbia University, New York, New York
,
Michael W. Varner
8   University of Utah, Salt Lake City, Utah
,
Dwight J. Rouse
9   University of Alabama at Birmingham, Birmingham, Alabama
,
John M. Thorp Jr.
10   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
,
Anthony Sciscione
11   Drexel University, Philadelphia, Pennsylvania
,
Patrick Catalano
12   Case Western Reserve University-MetroHealth Medical Center, Cleveland, Ohio
,
Margaret Harper
13   Wake Forest University Health Sciences, Winston-Salem, North Carolina
,
George Saade
14   University of Texas Medical Branch, Galveston, Texas
,
Steve N. Caritis
15   University of Pittsburgh, Pittsburgh, Pennsylvania
,
Yoram Sorokin
16   Wayne State University, Detroit, Michigan
,
Alan M. Peaceman
17   Northwestern University, Chicago, Illinois
,
for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network › Author Affiliations
Further Information

Publication History

20 June 2012

14 September 2012

Publication Date:
27 December 2012 (online)

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Abstract

Objective To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes.

Study Design This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL.

Results Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results.

Conclusion A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.

Keywords

low glucose screening test - neonatal hypoglycemia
 

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