Diabetologie und Stoffwechsel 2014; 9(1): R1-R8
DOI: 10.1055/s-0034-1365940
DuS-Refresher
© Georg Thieme Verlag KG Stuttgart · New York

Epidemiologie des Diabetes – aktuelle Zahlen

T. Tamayo
,
W. Rathmann
Further Information

Publication History

Publication Date:
17 February 2014 (online)

Zusammenfassung

In Deutschland sind verlässliche Daten zur Diabetesepidemiologie nach wie vor rar. Insbesondere zum nicht diagnostizierten Diabetes liegen auf der Basis von oralen Glukosetoleranztests keine deutschlandweiten Schätzungen vor. Zur Beurteilung der Diabetesprävalenz werden daher unterschiedliche Datenquellen herangezogen, deren methodische Vor- und Nachteile beachtet werden müssen. Insgesamt lassen die Studienergebnisse darauf schließen, dass insbesondere der Typ-2-Diabetes in Deutschland weit verbreitet ist. Im IDF-Atlas 2013 rangiert Deutschland europaweit sogar an zweiter Stelle, was die absolute Zahl an Diabetesfällen angeht. Darüber hinaus sind erhebliche regionale Unterschiede festzustellen mit einer deutlich höheren Prävalenz im Nordosten und Osten Deutschlands gegenüber dem Süden. Während sich die Versorgungssituation und die Therapieoptionen in den letzten Jahren insgesamt verbessert haben, ist die Mortalität bei Patienten mit Typ-2-Diabetes im Vergleich zur Gesamtbevölkerung immer noch erhöht.

Abstract

In Germany, valid epidemiological data for full accounting of type 2 diabetes prevalence including undiagnosed and diagnosed diabetes is still not available on nationwide level. Therefore, heterogeneous study types are used to determine the current epidemiological situation of diabetes in Germany. The current article gives an overview on the available data and discusses pros and cons of different methodological approaches. Overall, the available data suggest that numbers of type 2 diabetes are especially high in Germany, even ranking second for number of cases comparing all European countries in the IDF-Atlas 2013. Yet substantial regional differences exist with a considerably higher prevalence in the northeastern regions than in the south of Germany. While treatment options for type 2 diabetes and its complications have increased during the last years, overall mortality is still increased in persons with diabetes in comparison to the general population.

 
  • Literatur

  • 1 Cowie CC, Rust KF, Ford ES et al. Full accounting of diabetes and pre-Diabetes in the U. S. population in 1988–1994 and 2005–2006. Diabetes Care 2009; 32: 287-294
  • 2 World Health Organisation. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Report of a WHO consultation. Geneva: WHO; 1999
  • 3 Rathmann W, Haastert B, Icks A et al. High prevalence of undiagnosed diabetes mellitus in Southern Germany: target populations for efficient screening: the KORA survey 2000. Diabetologia 2003; 46: 182-189
  • 4 Heidemann C, Du Y, Schubert I et al. Prävalenz und zeitliche Entwicklung des bekannten Diabetes mellitus. Bundesgesundheitsblatt – Gesundheitsforschung – Gesundheitsschutz 2013; 56: 668-677
  • 5 IDF Diabetes Atlas. 6th ed. Brussels: International Diabetes Federation; 2013
  • 6 Tamayo T, Rosenbauer J, Wild SH et al. Diabetes in Europe: An update for 2013 for the IDF Diabetes Atlas. Diabetes Res Clin Pract 2013; Nov 27 [Epub ahead of print]
  • 7 Hauner H, Hanisch J, Bramlage P et al. Prevalence of undiagnosed type-2-diabetes mellitus and impaired fasting glucose in German primary care: data from the German Metabolic and Cardiovascular Risk Project (GEMCAS). Exp Clin Endocrinol Diabetes 2008; 116: 18-25
  • 8 Schipf S, Werner A, Tamayo T et al. Regional differences in the prevalence of known type 2 diabetes mellitus in 45–74 years old individuals: Results from six population-based studies in Germany (DIAB-CORE Consortium). Diabet Med 2012; 29: e88-e95
  • 9 Robert Koch-Institut Hrsg. Daten und Fakten: Ergebnisse der Studie „Gesundheit in Deutschland aktuell 2010“. Beiträge zur Gesundheitsberichterstattung des Bundes. Berlin: RKI; 2012
  • 10 Wilke T, Ahrendt P, Schwartz D et al. Incidence and prevalence of type 2 diabetes mellitus in Germany: an analysis based on 5.43 Million patients. Dtsch Med Wochenschr 2013; 138: 69-75
  • 11 Schipf S, Ittermann T, Tamayo T et al. Regional differences in the incidence of known type 2 diabetes mellitus in Germany. Diabetologia 2013; 56 (Suppl. 01) 126-127
  • 12 Maier W, Holle R, Hunger M et al. The Diabetes Collaborative Research of Epidemiologic Studies DIAB-CORE consortium. The impact of regional deprivation and individual socio-economic status on the prevalence of type 2 diabetes in Germany. A pooled analysis of five population-based studies. Diabet Med 2013; 30: e78-e86
  • 13 Müller G, Kluttig A, Greiser KH et al. Regional and neighborhood disparities in the odds of type 2 diabetes: results from 5 population-based studies in Germany (DIAB-CORE Consortium). Am J Epidemiol 2013; 178: 221-230
  • 14 Sallis JF, Floyd MF, Rodriguez DA et al. Role of built environment in physical activity, obesity and cardiovascular disease. Circulation 2012; 125: 729-737
  • 15 Rosenbauer J, Bächle C, Stahl A. for German Pediatric Surveillance Unit, DPV Initiative, German Competence Network Diabetes mellitus. et al. Prevalence of type 1 diabetes mellitus in children and adolescents in Germany. Diabetologia 2012; 55 (Suppl. 01) S369
  • 16 Rosenbauer J, Stahl A. Häufigkeit des Diabetes mellitus im Kindes- und Jugendalter in Deutschland. Diabetologe 2010; 6: 177-189
  • 17 Rosenbauer J, Stahl A, Bächle C. in Kooperation mit ESPED, DPV-Initiative und Kompetenznetz Diabetes. et al. Inzidenztrend des Typ 2-Diabetes mellitus bei Kindern und Jugendlichen in Nordrhein-Westfalen. Diabetologie Stoffwechsel 2012; S1-S13
  • 18 Herder C, Schmitz-Beuting C, Rathmann W et al. Prevalence of impaired glucose regulation in German school-leaving students. Int J Obes (Lond) 2007; 31: 1086-1088
  • 19 The STOPP-T2D Prevention Study Group. Presence of diabetes risk factors in a large US eighth-grade cohort. Diabetes Care 2006; 29: 212-217
  • 20 Icks A, Dickhaus T, Hörmann A et al. Lower incidence of myocardial infarction in non-diabetic subjects and in diabetic women, but not in diabetic men, in the population aged 25 to 74 years. Findings from the MONICA/KORA myocardial infarction registry in Southern Germany, 1985–2006. Diabetologia 2009; 52: 1836-1841
  • 21 Icks A, Haastert B, Trautner C et al. Incidence of lower-limb amputations in the diabetic compared to the non-diabetic population. Findings from nationwide insurance data, Germany, 2005–2007. Exp Clin Endocrinol Diabetes 2009; 117: 500-504
  • 22 Seshasai SR, Kaptoge S, Thompson A. Emerging Risk Factors Collaboration. et al. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med 2011; 364: 829-841
  • 23 Rückert IM, Schunk M, Holle R et al. Blood pressure and lipid management fall far short in persons with type 2 diabetes: results from the DIAB-CORE Consortium including six German population-based studies. Cardiovasc Diabetol 2012; 11: 50
  • 24 Hu FB, Stampfer MJ, Haffner SM et al. Elevated risk of cardiovascular disease prior to clinical diagnosis of type 2 diabetes mellitus. Diabetes Care 2002; 25: 1129-1134
  • 25 Meisinger C, Strassburger K, Heier M et al. Prevalence of undiagnosed diabetes and impaired glucose regulation in 35–39-year-old individuals in Southern Germany: the KORA F4 Study. Diabet Med 2010; 27: 360-362
  • 26 Kerner W, Brückel J. Definition, Klassifikation und Diagnostik des Diabetes mellitus. Diabetologie 2012; 7: S84-S87