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Synlett 2014; 25(16): 2341-2344
DOI: 10.1055/s-0034-1379213
DOI: 10.1055/s-0034-1379213
letter
A Highly Efficient Synthesis of 2,5-Disubstituted Furans from Enyne Acetates Catalyzed by Lewis Acid and Palladium
Authors
Further Information
Publication History
Received: 02 June 2014
Accepted after revision: 11 July 2014
Publication Date:
08 September 2014 (online)
Abstract
A highly efficient synthesis of a wide range of 2,5-disubstituted furans from enyne acetates is described. The reactions are conducted by using Lewis acid and palladium catalyst and provide symmetrical and unsymmetrical products in good to excellent yields, with broad substrate scope, including a variety of aromatic and aliphatic substituents in the 2- and 5-position of the furan ring.
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10.1055/s-00000083.
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