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Synfacts 2015; 11(4): 0387
DOI: 10.1055/s-0034-1380468
DOI: 10.1055/s-0034-1380468
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
Ruthenium-Catalyzed Z-Selective Cross-Metathesis of Allylic Alcohols
Further Information
Publication History
Publication Date:
18 March 2015 (online)

Significance
The authors describe a ruthenium complex catalyzed Z-selective cross-metathesis to afford (Z)-allylic alcohols. The reaction conditions are very mild and a wide range of functional groups (for example, aldehydes, carboxylic acids, phenols, and enol ethers) is tolerated.
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Comment
Using a ruthenium–disulfide complex, highly valuable (Z)-alkenes are obtained from easily available alkenes and (Z)-allylic alcohols. Theoretical studies provide a better understanding of this catalyst design.
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