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Am J Perinatol 2017; 34(01): 19-25
DOI: 10.1055/s-0036-1584151
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Comparison of Passive and Servo-Controlled Active Cooling for Infants with Hypoxic-Ischemic Encephalopathy during Neonatal Transfers

Autoren

  • Nitin Goel

    1   Neonatal Transfer Service, Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, United Kingdom

  • Syed Makhtum Mohinuddin

    1   Neonatal Transfer Service, Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, United Kingdom
    2   Department of Neonatal Medicine, Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, United Kingdom
    3   School of Health Sciences, City University, London, United Kingdom

  • Nandiran Ratnavel

    1   Neonatal Transfer Service, Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, United Kingdom
    2   Department of Neonatal Medicine, Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, United Kingdom

  • Stephen Kempley

    2   Department of Neonatal Medicine, Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, United Kingdom
    4   Centre for Paediatrics, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom

  • Ajay Sinha

    2   Department of Neonatal Medicine, Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, United Kingdom
    4   Centre for Paediatrics, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom
Weitere Informationen

Publikationsverlauf

19. Dezember 2015

30. März 2016

Publikationsdatum:
16. Mai 2016 (online)

Auch verfügbar auf
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Abstract

Objective The recent availability of servo-controlled cooling equipment on transport makes it possible to commence active cooling at the referral unit for infants with hypoxic-ischemic encephalopathy. This study aimed to compare the temperature and transfer variables in passively and actively cooled babies.

Study Design This is a retrospective cohort study comparing two groups—passively cooled (July 2011 to August 2012) versus actively cooled group (September 2012 to June 2013), following introduction of active hypothermia using servo-controlled cooling mattress by the London Neonatal Transfer Service (NTS).

Results Seventy-six infants were passively cooled and 69 were actively cooled. There was a significant difference between the temperatures of the two groups at each point in the transfer episode: on arrival of NTS, during stabilization, during transfer, and at the receiving hospital. Median time to achieve target temperature was 30 (95% confidence interval [CI]: 23–37) minutes in actively cooled, significantly shorter in comparison to 130 (95% CI: 83–177) minutes in passively cooled babies. Of the 69 newborns, 62 (90%) had temperature within target range at receiving center in actively cooled group as compared with 30/76 (40%) in passively cooled group.

Conclusion The use of active cooling during neonatal transfer achieves target temperature in a shorter period and maintains better temperature stability.

Keywords

neonate - neonatal transfer - hypoxic-ischemic encephalopathy - therapeutic hypothermia - active cooling - servo-controlled cooling
 

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