Synthesis of Veliparib

Philip Kocienski

doi:10.1055/s-0039-1689870

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Synfacts 2019; 15(07): 0716
DOI: 10.1055/s-0039-1689870

Synthesis of Natural Products and Potential Drugs

Synthesis of Veliparib

Contributor(s):

Philip Kocienski

Further Information

Publication History

Publication Date:
17 June 2019 (online)

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Key words

veliparib - poly(ADP ribose) polymerase inhibitor - (R)-Boc-2-methylproline - memory of chirality - intramolecular enolate alkylation - benzimidazole ring formation