C–H Activation of Gaseous Alkanes

Paul Knochel; Ferdinand H. Lutter

doi:10.1055/s-0040-1705827

RSS-Feed abonnieren

Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.

https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml

Teilen / Bookmarken

Facebook Linkedin Weibo

PDF herunterladen

Synfacts 2020; 16(09): 1127
DOI: 10.1055/s-0040-1705827

Flow Chemistry

C–H Activation of Gaseous Alkanes

Rezensent(en):

Paul Knochel

,

Ferdinand H. Lutter

Laudadio G, Deng Y, van der Wal K, Ravelli D, Nuño M, Fagnoni M, Guthrie D, Sun Y, Noël T. * Eindhoven University of Technology, The Netherlands
C(sp³)–H Functionalizations of Light Hydrocarbons using Decatungstate Photocatalysis in Flow.

Science 2020;
369: 92-96

Crossref PubMed Suche in Google Scholar

› Weitere Informationen

Abstract
Volltext
Abbildungen

als PDF herunterladen Lizenzen und Reprints

Key words

photocatalysis - C–H functionalization - hydrocarbons

Significance

Noël and co-workers describe a photocatalytic C–H activation of gaseous alkanes and subsequent trapping with various Michael acceptors in continuous flow. The corresponding alkylated products were obtained in moderate to excellent yields.

Comment

Mechanistically, the authors propose an initial activation of the photocatalyst TBADT, which relaxes to its active form wO. A hydrogen abstraction forms a carbon-centered radical, which undergoes a 1,4-addition to a Michael acceptor. Hydrogen back-donation affords the alkylated product and regenerates the catalyst.

Publikationsverlauf

Artikel online veröffentlicht:
18. August 2020

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

Lizenzen und Reprints