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Synlett 2020; 31(15): 1523-1526
DOI: 10.1055/s-0040-1707199
letter
© Georg Thieme Verlag Stuttgart · New York

Facile Synthesis of β-Bromostyrenes by Direct Bromination of Styrenes with N-Bromosuccinimide and Sodium Persulfate

Yi Jing
a   School of Chemistry and Chemical Engineering, Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, Henan Normal University, Xinxiang, Henan 453007, P. R. of China   Email: xnchen@htu.edu.cn   Email: mayanna@htu.edu.cn
,
Yan Gao
a   School of Chemistry and Chemical Engineering, Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, Henan Normal University, Xinxiang, Henan 453007, P. R. of China   Email: xnchen@htu.edu.cn   Email: mayanna@htu.edu.cn
,
Qianyi Zhao
a   School of Chemistry and Chemical Engineering, Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, Henan Normal University, Xinxiang, Henan 453007, P. R. of China   Email: xnchen@htu.edu.cn   Email: mayanna@htu.edu.cn
,
Xuenian Chen∗
a   School of Chemistry and Chemical Engineering, Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, Henan Normal University, Xinxiang, Henan 453007, P. R. of China   Email: xnchen@htu.edu.cn   Email: mayanna@htu.edu.cn
b   College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan 450001, P. R. of China
,
Yan-Na Ma∗
a   School of Chemistry and Chemical Engineering, Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, Henan Normal University, Xinxiang, Henan 453007, P. R. of China   Email: xnchen@htu.edu.cn   Email: mayanna@htu.edu.cn
› Author AffiliationsThis work was supported by the National Natural Science Foundation of China (Nos. 21801065 and U180425).
Further Information

Publication History

Received: 23 May 2020

Accepted after revision: 11 June 2020

Publication Date:
27 July 2020 (online)

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Abstract

A new, direct, efficient, and transition-metal-free method is reported for the synthesis of β-bromostyrenes from styrenes by using N-bromosuccinimide as the brominating reagent and sodium persulfate (Na2S2O8) as the oxidant. This convenient and concise reaction is practical, operationally simple, and can be adapted for large-scale syntheses.

Key words

bromination - styrenes - bromosuccinimide - green chemistry - sodium persulfate - bromostyrenes

Supporting Information

    Supporting information for this article is available online at https://doi.org/10.1055/s-0040-1707199.
  • Supporting Information

Primary Data

    for this article are available online at https://doi.org/10.1055/s-0040-1707199 and can be cited using the following DOI: 10.4125/pd0119th.

  • Primary Data
 

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