Gesundheitswesen 2023; 85(08/09): 756
DOI: 10.1055/s-0043-1770412
Abstracts
Vorträge
COVID-19

The effect of a COVID-19 infection on acute myocardial infarction: a rapid review

Authors

  • Karla Romero Starke

    1   Institute and Policlinic for Occupational and Social Medicine, Faculty of Medicine, TU Dresden, Dresden, Deutschland

  • Pauline Kaboth

    1   Institute and Policlinic for Occupational and Social Medicine, Faculty of Medicine, TU Dresden, Dresden, Deutschland

  • Natalie Bianca Rath

    1   Institute and Policlinic for Occupational and Social Medicine, Faculty of Medicine, TU Dresden, Dresden, Deutschland

  • Albert Nienhaus

    2   Department of Occupational Medicine, Toxic Substances and Health Research, Institution for Statutory Social Accident Insurance and Prevention in the Health Care and Welfare Services (BGW), Hamburg, Deutschland
    3   Competence Centre for Epidemiology and Health Services Research for Healthcare Professionals (CVcare), Institute for Health Service Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf, Hamburg, Deutschland

  • Andreas Seidler

    1   Institute and Policlinic for Occupational and Social Medicine, Faculty of Medicine, TU Dresden, Dresden, Deutschland
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    Background Diseases of various organs may appear after a COVID-19 infection. This rapid review aims to investigate whether there is an increased risk of acute myocardial infarction (AMI) after a SARS-CoV-2 infection as well as to characterize the risk at defined time intervals between infection and the onset of AMI.

    Methods The review protocol was registered with PROSPERO. We searched for observational studies in Medline, Embase, and medRxiv. One reviewer screened all titles/abstracts and full texts of the studies, while a second reviewer screened 20%. Two reviewers performed the extraction, risk of bias, and GRADE assessment. A meta-analysis was done to quantify the relative risk of AMI a year after follow-up and at defined time intervals post COVID-19 infection.

    Results Eight reports from six studies were included. There was an 80% increased risk of having an AMI throughout the follow-up period of five to twelve months (RR = 1.82, 95% CI 1.76-1.88). In the first day after a COVID-19 infection, the risk was highest (RR = 16.9 95% CI 16.7-17.0), and it decreased with time. After 14 months, the risk remained elevated (RR = 1.09, CI 95% CI 1.05-1.13).

    Conclusions Our results show a best-possible quantification of the risk of AMI after a SARS-CoV-2 infection. Since new studies on the topic are produced continually, it is appropriate to establish a “living review” to evaluate the evidence on long COVID, including cardiovascular outcomes.


     

    Publication History

    Article published online:
    22 August 2023

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