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Endoscopy 2002; 34(9): 715-720
DOI: 10.1055/s-2002-33443
DOI: 10.1055/s-2002-33443
Original Article
© Georg Thieme Verlag Stuttgart · New YorkEndoscopic Ultrasound-Guided Pancreatic Duct Aspiration: Diagnostic Yield and Safety
Further Information
Publication History
Submitted: 20 September 2001
Accepted after Revision: 25 April 2002
Publication Date:
26 August 2002 (online)
Background and Study Aims: Endoscopic ultrasound (EUS)-guided fine-needle aspiration provides useful diagnostic
material in solid and cystic pancreatic lesions. It is logical that EUS-guided pancreatic
duct aspiration may be useful in cases of suspected intraductal or duct-obstructing
tumors. We evaluated the safety and efficacy of EUS-guided pancreatic duct aspiration.
Patients and Methods: Twelve patients with dilated pancreatic ducts underwent EUS-guided duct aspiration.
Aspirates were submitted for cytology and mucin staining. Patients were followed for
up to 13 months.
Results: There were no procedure-related complications. Cytology was diagnostic in nine of
the 12 patients (six with intraductal papillary mucinous tumor, one with pancreatic
clonorchiasis, and two with obstructing solid pancreatic adenocarcinomas). Cytology
in the remaining three patients, all with solid obstructing masses, was nondiagnostic.
Overall, the diagnostic yield was 75 %; however, the yield was 100 % in patients without
extrinsic obstruction.
Conclusion: This preliminary experience suggests that EUS-guided pancreatic duct aspiration is
safe and can provide diagnostic material in a significant number of patients with
unexplained pancreatic duct dilation.
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S. Mallery, M.D.
Division of Gastroenterology · Hennepin County Medical Center
701 Park Avenue South, 865B · Minneapolis, MN 55415 · USA
Fax: + 1-612-904-4366
Email: shawn.mallery@co.hennepin.mn.us