Synfacts 2005(1): 0103-0103  
DOI: 10.1055/s-2005-872155
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Total Synthesis of Stephacidin A

Contributor(s): Philip Kocienski
P. S. Baran*, C. A. Guerrero, N. B. Ambhaikar, B. D. Hafensteiner
Scripps Research Institute, La Jolla, USA
Further Information

Publication History

Publication Date:
21 September 2005 (online)

Significance

Stephacidins A and B are metabolites of Aspergillus ochraceus. Both are potent antitumour agents that appear to have a novel mechanism of action.