Postoperative Chylous Ascites in a Neonate Treated Successfully with Octreotide: Bile Sludge and Cholestasis

Alexander Andreou; Maria Papouli; Vaso Papavasiliou; Maria Badouraki

doi:10.1055/s-2005-872588

American Journal of Perinatology, Table of Contents

Am J Perinatol 2005; 22(8): 401-404
DOI: 10.1055/s-2005-872588

Postoperative Chylous Ascites in a Neonate Treated Successfully with Octreotide: Bile Sludge and Cholestasis

Alexander Andreou¹ , Maria Papouli¹ , Vaso Papavasiliou¹ , Maria Badouraki²

¹Department of Neonatology, Hippokration General Hospital, Thessaloniki, Greece
²Department of Radiology, Hippokration General Hospital, Thessaloniki, Greece

Abstract

ABSTRACT

We report a case of postoperative chylous ascites after surgical repair of congenital diaphragmatic hernia (CDH) in a full-term neonate. Treatment with subcutaneously administered octreotide resulted in rapid resolution of chylous effusion. Octreotide treatment had transient side effects, with bile sludge and cholestasis.

KEYWORDS

Chylous ascites - octreotide - bile sludge - cholestasis

Full Text

References

REFERENCES

1 Tilmont P, Alessandri J L, Duthoit G, Rossi-Farrer C, Roge-Wolter M. Epanchement chyleux après cure chirurgicale d' une hernie diaphragmatique chez 2 nouveau-nes. Arch Fr Pediatr. 1993; 50 783-786
2 Nakayama D K. Congenital diaphragmatic hernia. In: Nakayama DK, Bose CL, Chescheir NC, Valley RD Critical Care of Surgical Newborn. Armonk, NY; Futura Publishing 1997: 193
3 Goyal A, Smith N, Jesudason E, Kerr S, Losty P. Octreotide for treatment of chylothorax after repair of congenital diaphragmatic hernia. J Pediatr Surg. 2003; 38 E19-E20
4 Cheung Y, Leung M P, Yip M. Octreotide for treatment of postoperative chylothorax. J Pediatr. 2001; 139 157-159
5 Young S, Dalgleish S, Eccleston A, Akierman A, McMillan D. Severe congenital chylothorax treated with octreotide. J Perinatol. 2004; 24 200-202
6 Coulter D M. Successful treatment with octreotide of spontaneous chylothorax in a premature infant. J Perinatol. 2004; 24 194-195
7 Caty M G, Hilfiker M L, Azizkhan R G, Glick P L. Successful treatment of congenital chylous ascites with a somatostatin analogue. Pediatr Surg Int. 1996; 11 396-397
8 Unger S W, Chandler J G. Chylous ascites in infants and children. Surgery. 1983; 93 455-461
9 Bhatia C, Pratap U, Slavik Z. Octreotide therapy: a new horizon in treatment of iatrogenic chyloperitoneum. Arch Dis Child. 2001; 85 234-235
10 Al-Tawil K, Ahmed G, Al-Hathal M, Al-Jarallah Y, Campbell N. Congenital chylothorax. Am J Perinatol. 2000; 17 121-126
11 Mitsunaga T, Yoshida H, Iwai J et al.. Successful surgical treatment of two cases of congenital chylous ascites. J Pediatr Surg. 2001; 36 1717-1719
12 Camoglio F S, Dipaola G, Cervellione R M et al.. Treatment of neonatal chylous ascites using a modified Denver peritoneovenous shunt:a case report. Pediatr Med Chir. 2003; 25 145-147
13 te Pas A B, vd Ven K, Stokkel M P, Walther F J. Intractable congenital chylous ascites. Acta Paediatr. 2004; 93 1403-1405
14 Man D W, Spitz L. The management of chylous ascites in children. J Pediatr Surg. 1985; 20 72-75
15 Wasmuth-Pietzuch A, Hansmann M, Bartmann P, Heep A. Congenital chylothorax: lymphopenia and high risk of neonatal infections. Acta Paediatr. 2004; 93 220-224
16 Arevalo R P, Bullabh P, Krauss A N, Auld P AM, Spigland N. Octreotide-induced hypoxemia and pulmonary hypertension in premature neonates. J Pediatr Surg. 2003; 38 251-253
17 Section 5 product information. In: Physicians' Desk Reference, 57th ed. Montvale, NJ; Thomson 2003: 2313-2315

Alex Andreou

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