Acute Myelogenous Leukemia Mimicking a Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome during Pregnancy: Case Report and Review of the Literature

Ramzi Aboujaoude; Jesus Alvarez; Manuel Alvarez; Abdullah Al Khan

doi:10.1055/s-2006-954955

American Journal of Perinatology, Table of Contents

Am J Perinatol 2007; 24(1): 001-004
DOI: 10.1055/s-2006-954955

Acute Myelogenous Leukemia Mimicking a Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome during Pregnancy: Case Report and Review of the Literature

Ramzi Aboujaoude¹ , Jesus Alvarez¹ , Manuel Alvarez² , Abdullah Al Khan²

¹New Jersey Medical School, University of Medicine and dentistry, Newark
²Hackensack University Medical Center, Hackensack, New Jersey

Abstract

ABSTRACT

Acute leukemia is a rare malignancy of pregnancy. When it develops, there are many complications to consider and management becomes exceedingly difficult. We report a case of acute myelogenous leukemia presenting as preeclampsia and fetal demise at 36 weeks of gestation. A 30-year-old multigravida presented with intrauterine fetal demise at 36 weeks' gestation, hypertension, and thrombocytopenia. The patient received platelet and packed red blood cell transfusion, with concurrent prophylactic magnesium sulfate and dexamethasone treatment. Following labor induction, the patient delivered a nonviable female fetus and suffered a stroke postpartum. Peripheral smear and flow cytometry revealed the patient had acute myeloid leukemia with prominent monocytic differentiation. The patient expired on postpartum day six. Acute leukemia during the pregnancy is associated with an unfavorable outcome.

KEYWORDS

Pregnancy - thrombocytopenia - acute myelogenous leukemia

Full Text

References

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