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Synfacts 2007(1): 0038-0038  
DOI: 10.1055/s-2006-955673
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart · New York

Preparation of Novel Tetrathia[7]helicenes

Contributor(s): Timothy M. Swager, Julian M. W. Chan
E. Licandro, C. Rigamonti, M. T. Ticozzelli, M. Monteforte, C. Baldoli, C. Giannini, S. Maiorana*
Università degli Studi di Milano, Italy
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Publication History

Publication Date:
15 December 2006 (online)

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Significance

Synthetic routes leading to functionalized tetrathia[7]helicenes have been developed. Initial formation of 3 via double Suzuki coupling is followed by functionalization and ring-closure (or with steps reversed) to give the desired helicenes in modest to good yields. Intermediate 3 could also be accessed by McMurry coupling (not shown). The physical and chemical properties of the helicenes are currently being studied, and attempts to prepare optically active samples are also underway.