Synfacts 2007(3): 0339-0339  
DOI: 10.1055/s-2007-968220
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

Magnetic Nanoparticle-Supported Phase-Transfer Catalysts

Contributor(s): Yasuhiro Uozumi, Yohei Oe
M. Kawamura, K. Sato*
National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
Further Information

Publication History

Publication Date:
20 February 2007 (online)

Significance

New magnetically separable phase-transfer catalysts were successfully developed. Thus, the magnetic nanoparticle-supported ammonium salt 1 was prepared by the reaction of tributylamine with (3-iodopropyl)trimethoxysilane followed by immobilization of the resulting ammonium salt on Fe3O4 (eq. 1). The reaction of sodium phenoxide with 1-bromobutane was carried out in the presence of catalyst 1 at 100 °C for 12 h to give the n-butyl phenyl ether in 94% yield (eq. 2). The catalytic activity of 1 is comparable to TBAI (86% yield) and higher than polystyrene resin supported ammonium salt 2 (50% yield).