Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2007(4): 0342-0342
DOI: 10.1055/s-2007-968288
DOI: 10.1055/s-2007-968288
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York
Synthesis of (±)-Morphine
K. Uchida, S. Yokoshima, T. Kan, T. Fukuyama*
The University of Tokyo and University of Shizuoka, Japan
Further Information
Publication History
Publication Date:
23 March 2007 (online)
Significance
Noteworthy in this approach to a classic target is (1) the use of an intramolecular Heck reaction to install the quaternary center in E, and (2) the aldol-Michael cascade (E to F) which creates two rings.