Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2008(2): 0188-0188
DOI: 10.1055/s-2007-992471
DOI: 10.1055/s-2007-992471
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York
A Novel Complementary Synthesis of Multisubstituted Cyclopentenones via [3+2] Cyclization
J. Barluenga*, P. Barrio, L. Riesgo, L. A. López, M. Tomás
Universidad de Oviedo, Spain
Further Information
Publication History
Publication Date:
23 January 2008 (online)
Significance
The formal [3+2]-cycloaddition reaction between an alkenyl-Fischer carbene complex and internal alkynes was found to offer a straightforward access to trisubstituted cyclopent-2-enones with a novel substitution pattern that cannot be easily accessed by conventional methods.