Prognosis of congenital infantile cortical hyperostosis (Caffey's disease) is poor
particularly in premature babies. Two cases are presented of congenital Caffey's disease
in premature babies. The first baby was hydropic at birth and had cortical hyperostosis
involving the mandible and long bones of right upper limb and both lower limbs. The
second baby had cortical hyperostosis of the nasal bones causing severe nasal nonchoanal
stenosis that needed surgery, in addition to involvement of long bones of the four
extremities. Both babies recovered from the disease and were discharged home well.
These cases suggest that the improved outcome of congenital of infantile cortical
hyperostosis may reflect improvement of neonatal mechanical ventilation and availability
of neonatal total parenteral nutrition.
Caffey's disease - infantile cortical hyperostosis (ICH) - skeletal disorder
