Sonographic Evaluation of the Normal Developmental Anatomy of Fetal Cerebral Ventricles. IV.: The Posterior Horn

Israel Goldstein; E. Albert Reece; Gian-Luigi Pilu; John C. Hobbins

doi:10.1055/s-2007-999452

American Journal of Perinatology, Table of Contents

Am J Perinatol 1990; 7(1): 79-83
DOI: 10.1055/s-2007-999452

ORIGINAL ARTICLE

Sonographic Evaluation of the Normal Developmental Anatomy of Fetal Cerebral Ventricles. IV.: The Posterior Horn

Israel Goldstein, E. Albert Reece, Gian-Luigi Pilu, John C. Hobbins

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, and the Pathophysiology Unit, Department of Obstetrics and Gynecology, Bologna University, Bologna, Italy

Abstract

ABSTRACT

A prospective ultrasound study was conducted in 160 normal pregnant women with gestational ages ranging from 14 to 40 weeks. Several fetal biometric measurements were obtained, including the posterior horn width (PHW) and the cerebroposterior horn distance (CPHD) of the lateral ventricles. Curvilinear relationships were found between the gestational age and the ratio of the PHW/CPHD (r = 0.665, p < 0.0001); and the PHW/hemispheric width (HW), (r = 0.716, p < 0.0001) and also between the biparietal diameter and the PHW/CPHD ratio (r = 0.649, p < 0.0001), and the PHW/HW ratio (r = 0.732, p < 0.0001). A correlation in growth was also observed between the femur length and the PHW/CPHD (r = 0.660, p < 0.0001), and the PHW/HW (r = 0.734, p < 0.0001). Nomograms of the PHW, CPHD, and the ratio of PHW/CPHD against gestational age were generated. The establishment of normal indices of the posterior horn provides new, precise, and comprehensive data that will serve as a standard against which the evaluation of early abnormal ventricular growth and anomalous development of the central nervous system may be compared.

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