PDF herunterladen
Synfacts 2008(5): 0445-0445  
DOI: 10.1055/s-2008-1072702
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Norbadione A

Contributor(s): Philip Kocienski
Y. Bourdreaux, S. Nowaczyk, C. Billaud, A. Mallinger, C. Willis, M. Desage-El Murr, L. Toupet, C. Lion, T. Le Gall*, C. Mioskowski*
CEA, Gif-sur-Yvette, Université de Rennes and Université de Paris, France
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
23. April 2008 (online)

    Lizenzen und Reprints

Significance

Norbadione A is a mushroom pigment and an antioxidant. Following the Chernobyl disaster it was found that norbadione A forms complexes with cesium 137 causing its retention and concentration in edible mushrooms (W. Steglich Angew. Chem. Int. Ed. 1989, 28, 453). The synthesis depicted is based on the use of a double Suzuki-Miyaura coupling to join the the pulvinic acid derivative I to the naphtholactone H.