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Synfacts 2008(8): 0828-0828
DOI: 10.1055/s-2008-1078550
DOI: 10.1055/s-2008-1078550
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New York
Os(II) Pincer Complex for Asymmetric H2 and Transfer Hydrogenation
W. Baratta*, M. Ballico, G. Chelucci, K. Siega, P. Rigo
Università di Udine and Università di Sassari, Italy
Further Information
Publication History
Publication Date:
23 July 2008 (online)
Significance
Catalytic asymmetric H2 and transfer hydrogenation (TH) methods using Ru, Rh, and Ir complexes are well known. The authors have previously shown that several Os complexes display comparable activities compared to related Ru-based catalysts in TH of ketones (Chem. Eur. J. 2008, 14, 2557). In the present work, isolation of the first CNN Os pincer complexes and their application in hydrogenation reactions are reported. Notably, these catalysts display tremendous levels of activity with loadings as low as 0.001 mol% and TOF of ˜105 h-¹.