DOI: 10.1055/s-00000131

Synfacts

Issue 08 · Volume 8 · August 2012 DOI: 10.1055/s-002-23511

Synform

A75
Zanda, Matteo: SYNFORM ISSUE 2012/08

Synthesis of Natural Products and Potential Drugs

z811
All PDFs of this category
0811
Synthesis of a CB1 Cannabinoid Receptor Antagonist
0812
Synthesis of (S)-Duloxetine
0813
Synthesis of (–)-Berkelic Acid
0814
Synthesis of Anominine and Tubingensin A
0815
Synthesis of a Telithromycin Analogue
0816
Synthesis of (–)-13-Oxyingenol and Its Natural Derivative
0817
Synthesis of a Glucosylceramide Synthase Inhibitor
0818
Synthesis of (+)-Gelsemine
0819
Synthesis of an Akt Kinase Inhibitor
0820
Synthesis of Pellasoren A
0821
Synthesis of (+)-Chimonanthine
0822
Synthesis of (R)-Ramatroban
0823
Synthesis of PF-00951966
0824
Synthesis of a Glucokinase Activator
0825
Synthesis of LY500307
0826
Synthesis of Doxercalciferol
0827
Synthesis of (–)-Mersicarpine
0828
Synthesis of AZD6906

Synthesis of Heterocycles

z829
All PDFs of this category
0829
Au-Catalyzed Carbonyl Migration for the Synthesis of Azepinoindol-1-ones
0830
One-Pot Pd-Catalyzed Synthesis of Isoquinolines and Furo/Thienopyridines
0831
Synthesis of Isoquinolin-1(2H)-ones via Pd-Catalyzed Isocyanide Coupling
0832
Synthesis of Piperazine-2,5-diones via a Convenient Dieckmann Cyclization
0833
A Cu-Catalyzed Double C–N Coupling Approach to Cinnolines
0834
Functionalized Enantioenriched Dihydropyrans by [4+2] Cycloaddition
0835
DABCO-Mediated [4+2] Annulation Approach to 2,3-Dihydropyran-4-ones
0836
Selectivity in Palladium-Catalyzed Carboesterification – Amides versus Esters
0837
Synthesis of Benzofuro[3,2-d]pyrimidines from 3-Chlorochromones
0838
Synthesis and Suzuki Coupling of 2-Aryl-Trisubstituted Oxazoles
0839
Indoloazocines via a Sequential Ugi–Gold-Catalyzed Hydroarylation
0840
Polysubstituted Pyridines via Re-Catalyzed Alkyne Insertion
0841
Synthesis of 3-Carboxylated Indoles from 2-Ethynylanilines and CO2
0842
Iron-Catalyzed Substitution of Benzoxazoles and Benzothiazoles
0843
Palladium-Catalyzed Synthesis of Indoles via Oxidative C–H Activation

Synthesis of Materials and Unnatural Products

z845
All PDFs of this category
0845
Polyethylene from Trimethylsulfoxonium Halide in Water
0846
Stabilized Heptacene for n-Type Materials
0847
Large Twisted Acenes
0848
Stable Boron–Boron Triple Bond
0849
Highly Flexible COT
0850
π-Conjugated Polycycle Containing Boron
0851
Zipping Oligo-Alkynes into Aromatic Ribbons
0852
Sensing Chirality of α-Hydroxyl Carboxylic Acids with a Fluorescent Polymer
0853
Activated Alumina Activates C–F Bonds: A New Route to PAHs
0854
Synthesis of New Types of Subporphyrins
0855
π-Expanded Diketopyrrolopyrrole Dyes
0856
Diastereoselective [2+2+2] Cycloisomerization in the Synthesis of Helicenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z857
All PDFs of this category
0857
Palladium-Catalyzed Asymmetric Quaternary Stereocenter Formation
0858
Sc-Catalyzed Enantioselective Allylation of Isatins
0859
Rh-Catalyzed Addition of Arylboronic Acids to α,β-Unsaturated Sulfonyls
0860
Asymmetric, Titanium-Mediated Aldol-Type Enamide–Aldehyde Cyclization
0861
Copper-Catalyzed Highly Diastereoselective [3+3] Cycloaddition
0862
Rh-Catalyzed Amination of Tertiary Allylic Trichloroacetimidates
0863
Zinc–ProPhenol-Catalyzed Asymmetric Spirannulation of α-Hydroxyoxindoles
0864
Chiral Tin Dibromide Catalyzed Enantioselective N-Nitroso Aldol Reaction
0865
Asymmetric Allylic Alkylation of Pyrroles and 4,7-Dihydroindoles
0866
Asymmetric Epoxidations of Enones Mediated by Non-Heme Iron Catalysts
0867
Enantioselective Synthesis of Pyridylcarbinols
0868
Copper-Catalyzed Synthesis of Heterobicyclo[3.1.1]heptan-6-ones
0869
Iridium-Catalyzed Asymmetric Synthesis of syn-3-Fluoro-1-alcohols
0870
Rhodium-Catalyzed Cyclopropanation of Azido Alkenes
0871
Ru-Catalyzed Asymmetric Hydrogenation of Unsaturated β-Keto Esters
0872
Inversion of Chirality by Redox-Induced Catalyst Reconfiguration
0873
Palladium-Catalyzed Asymmetric Allylic Alkylation of Pyrroles
0874
Palladium-Catalyzed Asymmetric 6-endo Cyclization of Dienamides
0875
Au-Catalyzed Enantioselective Cope Rearrangement
0876
Ion-Paired Ligands for Palladium-Catalyzed Asymmetric Allylation
0877
Catalytic Hydrogenation for the Preparation of Alkyl Boron Compounds
0878
Multinuclear Cu-Catalyzed Asymmetric Conjugate Addition
0879
Pd-Catalyzed Asymmetric Synthesis of Indolines
0880
Palladium-Catalyzed Asymmetric Synthesis of Dibenzosiloles
0881
Ru-Catalyzed Enantioselective Addition of Amines to Styrenes
0882
Ni-Catalyzed Ring Opening of Cyclopropanes with Amines
0883
Scandium-Catalyzed Enantioselective Epoxidation of Chalcones
0884
Au(I)-Catalyzed Asymmetric Hydroamination of Racemic Allenes
0885
Cu-Catalyzed Reductive Coupling of Alkenylazaarenes with Ketones

Metal-Mediated Synthesis

z887
All PDFs of this category
0887
Cu-Catalyzed/Ru-Photocatalyzed Trifluoromethylation of Boronic Acids
0888
Co-Catalyzed Asymmetric Addition of Acetylenes to Benzonorbornadienes
0889
Alkylmagnesium Reagents from Boron–Magnesium Exchange
0890
One-Pot Synthesis of 4-Aryl-N-methyl-1,2,3,4-tetrahydroisoquinolines
0891
β-Arylation of Ketones by a 1,4-Addition Sequence under Flow Conditions
0892
Asymmetric Ring Opening of Aziridines with Halides
0893
Amide-Forming Ligation of Acyltrifluoroborates and Hydroxylamines
0894
Novel Lewis Acid ATNP for Vinylogous Aldol Reactions
0895
Asymmetric Synthesis of Secondary Nitriles via Negishi Cross-Coupling
0896
Intramolecular Vinylation of Organolithiums
0897
Synthesis of Fluorinated Cyclopropanes
0898
Mes2Mg-Mediated Shapiro Reactions of Tosylhydrazones
0899
New Iron Thiolate Complexes for Cross-Coupling Reactions
0900
Synthesis of 1,4-Dihydropyridines and Pyridines out of N-Allyl Ynamides
0901
Ni-Catalyzed Alkylation of Purines and Benzimidazoles with Grignard Reagents

Organo- and Biocatalysis

z903
All PDFs of this category
0903
Organocatalytic Approach to N−H Insertion Reactions
0904
Vinylogous Michael Addition Catalyzed by Cinchona Thiourea
0905
Catalytic Asymmetric 1,6-Addition of Alkyl Thiol to Cyclic Dienones
0906
Regiodivergent Asymmetric Allylic Alkylation
0907
Asymmetric Fluorination of Enamides
0908
α-Vinylation of Aldehydes via Combination of Copper and Aminocatalysis
0909
[4+2] Cycloaddition Catalyzed by Quinine-Derived Primary Amine
0910
Modified Cinchona Amine Catalyzed Epoxidation of 2-Cyclopentenones
0911
Catalytic Asymmetric Ring-Opening Reactions of Aziridines
0912
Enzymatic Reductive Amination of Diketones

Polymer-Supported Synthesis

z913
All PDFs of this category
0913
Asymmetric Michael Addition of Aldehydes to Nitroalkenes Using JH-CPP
0914
Aerobic Oxidation of α-Hydroxy Ketones with CaO
0915
Epoxidation of Olefins with a Silica-Supported Peracid in Flowing scCO2
0916
Au/MoOx-Catalyzed Aerobic Oxidation of Alcohols
0917
A RuNPs-Based Supramolecular Hydrogel for Hydrogenation of Alkenes
0918
DMAP-Embedded Nanoporous Conjugated Polymer
0919
Asymmetric Hydrogenation of Ketones with Cp*RhTsDPEN-POSS
0920
Direct Synthesis of Vitamin K4 Using Bifunctional Heterogeneous Catalyst
0921
One-Pot Sonogashira–Click Coupling with a Cu-Pd MOF Catalyst
0922
Suzuki Coupling with Polymer-Supported Pd Nanoparticles in Water
0923
A3-Coupling Using TiO2-Supported Copper Nanoparticles
0924
Asymmetric Aldol Reaction with a Polymeric Organocatalyst
0925
Ring Opening of Epoxides Catalyzed by Graphene Oxide
0926
Hydration of Nitriles to Amides with Fe3O4@SiO2–Ru Catalyst

Addenda and Errata

0927
De Houwer, J.; Tehrani, K. Abbaspour; Maes, B. U. W.: Synthesis of Acrivastine
0927
Mulla, S. A. R.; Inamdar, S. M.; Pathan, M. Y.; Chavan, S. S.: Ullmann Diaryl Etherification with Copper Fluorapatite

Erratum

0927
Adams, G. L.; Carroll, P. J.; Smith, A. B.: Synthesis of (+)-Scholarisine A