DOI : 10.1055/s-00000094

Zeitschrift für Gastroenterologie

Ausgabe 12 · Volume 53 · Dezember 2015 DOI: 10.1055/s-005-30542


32. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber
Düsseldorf, 22. – 23. Januar 2016

Kongresspräsident: Prof. Dr. Dieter Häussinger
Abstracts (HTML) Autorenliste
A3_1
Bohner, A; Rebholz, C; Hall, RA; Lammert, F; Weber, SN: Die lithogene Variante D19 H im Cholsterintransporter Abcg8 führt zu verminderter Phospholipidsekretion in Mäusen
A3_2
Hermanns, HM; Schubert, S; Schäfer, C; Walter, S; Dorbath, D; Mais, C; Jahn, D; Geier, A: Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner
A3_3
Henkel, J; Coleman, CD; Jöhrens, K; Kuna, M; Grüner, I; Püschel, GP: Development of a new modified western diet to induce NASH with obesity and insulin resistance in mice
A3_4
Karababa, A; Aygul, S; Görg, B; Häussinger, D: Ammoniak induziert NADPH-Oxidase 4- vermittelt oxidativen Stress in kultivierten Rattenastrozyten
A3_5
Groos-Sahr, K; Albrecht, U; Shafigullina, A; Görg, B; Häussinger, D: Ammoniak hemmt die LPS-induzierte Mikrogliaaktivierung und Transkription pro-inflammatorischer Zytokine in Astrozyten/Mikroglia Kokulturen
A3_6
Oenarto, J; Karababa, A; Castoldi, M; Bidmon, HJ; Görg, B; Häussinger, D: Ammoniak induzierte miRNA Expressionsänderungen in kultivierten Rattenastrozyten
A3_7
Ibrahim, S; Dayoub, R; Melter, M; Weiss, T: Antiapoptotic and antioxidative protein ALR in Cholestatic Liver Diseases – Do bile acids regulate ALR expression via Egr1?
A3_8
Schlune, A; vom Dahl, S; Häussinger, D; Ensenauer, R; Mayatepek, E: Arginase 1 deficiency: long-term follow-up of the original patients
A3_9
Stindt, J; Tiller, T; Dröge, C; Brackertz, B; Kriegel, C; Klattig, J; Häussinger, D; Kubitz, R; Keitel, V: Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump
A3_10
Jiao, L; Gan-Schreier, H; Wei, W; Tuma-Kellner, S; Stremmel, W; Chamulitrat, W: Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation
A3_11
Liebe, R; Krawczyk, M; Raszeja-Wyszomirska, J; Kruk, B; Preis, R; Trottier, J; Barbier, O; Milkiewicz, P; Lammert, F: Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)
A3_12
Liebe, R; Krawczyk, M; Zimmer, V; Jüngst, C; Lammert, F: The power of NGS: Results from a dedicated sequencing panel of 24 genes in 40 patients with cholestatic liver disease
A3_13
Castoldi, M; Kordes, C; Sawitza, I; Häussinger, D: Differential modulation of vesicular and non-vesicular associated microRNAs isolated from sera of partially hepatectomized rats
A3_14
Khawar, MB; Sheikh, N: Effect of paper industry leachate on various serological indices and serum proteins
A3_15
Dayoub, R; Melter, M; Vlaic, S; Guthke, R; Weiss, T: Hepatic gene expression profile characterizes high levels of liver regeneration related genes in nonalcoholic fatty liver disease
A3_16
Levada, K; Guldiken, N; Vella, G; James, LP; Haybaeck, J; Kiemer, AK; Kessler, SM; Trautwein, C; Strnad, P: Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury
A3_17
Mahli, A; Thasler, WE; Patsenker, E; Müller, S; Stickel, F; Müller, M; Seitz, HK; Cederbaum, AI; Hellerbrand, C: Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro
A3_18
Riedel, A; Hornung, M; Schlitt, HJ; Geissler, EK; Werner, JM: Innate Immune Cell Activation in a Human in-vitro Model of Nonalcoholic Steatohepatitis (NASH)
A3_19
Manowsky, J; Camargo, R; Henkel, J; Püschel, GP: Insulin-induced cytokine production as potential contributor to hepatic insulin resistance
A3_20
Cubero, FJ; Zoubek, ME; Hu, W; Zhao, G; Peng, J; Nevzorova, YA; Al Masaoudi, M; Bechmann, LP; Boekschoten, MV; Muller, M; Preisinger, C; Gassler, N; Canbay, AE; Luedde, T; Davis, RJ; Liedtke, C; Trautwein, C: Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung
A3_21
Cubero, FJ; Peng, J; Hatting, M; Zhao, G; Zoubek, ME; Macias-Rodriguez, RU; Ruiz-Margain, A; Reißing, J; Zimmermann, HW; Gassler, N; Luedde, T; Liedtke, C; Trautwein, C: Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase
A3_22
Stremmel, W; Staffer, S; Wannhoff, A; Pathil-Warth, A; Chamulitrat, W: Lysophosphatidylcholine (LPC) as central player for control of hepatocellular fatty acid influx
A3_23
Graffmann, N; Kawala, MA; Ring, S; Wruck, W; Adjaye, J: Modelling of human nonalcoholic fatty liver disease with hepatocyte like cells derived from pluripotent stem cells
A3_24
Döring, P; Pilo, GM; Calvisi, DF; Dombrowski, F: Nuclear ErbB2 Expression of Hepatocytes in Alcoholic Steatohepatitis as Response to Cellular Stress Events
A3_25
Kristin, S; Madlen, MS; Thomas, M; Rolf, G: Regulation des Energiestoffwechsels in Hepatozyten durch Morphogene
A3_26
Sommerfeld, A; Mayer, PGK; Cantore, M; Häussinger, D: Regulation of Plasma Membrane Localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by Hyperosmolarity and Tauroursodeoxycholate
A3_27
Dröge, C; Kluge, S; Häussinger, D; Kubitz, R; Keitel, V: Sequencing of ATP8B1, ABCB11 and ABCB4 revealed 135 genetic variants in 374 unrelated patients with suspected intrahepatic cholestasis
A3_28
Schierwagen, R; Maybüchen, L; Klein, S; Uschner, FE; Hittatiya, K; Plat, J; Nickenig, G; Strassburg, CP; Lütjohann, D; Zimmer, S; Trebicka, J: Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät
A3_29
Klindt, C; Deutschmann, K; Reich, M; Herebian, D; Mayatepek, E; Häussinger, D; Keitel, V: TGR5 knockout mice are highly susceptible to LCA induced liver damage
A3_30
Nakhaeizadeh, H; Nakhaei-Rad, S; Amin, E; Kordes, C; Häussinger, D; Ahmadian, MR: The impact of the interaction between Embryonic stem cell-expressed Ras and Arginase-1 in hepatic stellate cells
A3_31
Lettmann, KA; Hardtke-Wolenski, M: The liver microcirculation might be important in promoting autoimmune hepatitis via maintaining an inflammatory cytokine milieu – A mathematical model study
A3_32
Paluschinski, M; Häussinger, D; Castoldi, M: The liver specific microRNA-122 modulates hepatic response to infection and inflammation by antagonizing YY1, FoxP3, Nfr1 and E2F4 molecular networks
A3_33
Drescher, HK; Berger, C; Fischer, P; Berres, ML; Kroy, DC; Streetz, KL; Trautwein, C; Sahin, H: The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo
A3_34
Hoffmann, V; Bowe, A; Curth, HM; Goeser, T; Nierhoff, D: Different mouse models of oval cell induction can lead to reactivation of the oncofetal marker Neighbor of Punc E 11
A3_35
Godoy, P; Schmidt-Heck, W; Campos, G; Widera, A; Stoeber, R; Weiss, T; Nussler, A; Damm, G; Küppers-Munther, B; Hay, DC; Hengstler, JG: Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro
A3_36
Rennert, C; Matz-Soja, M; Gebhardt, R: Up and Down of Hedgehog Signaling leads to Down and Up of Steroidogenesis in the Liver
A3_37
Matz-Soja, M; Rennert, C; Gebhardt, R: Konnex von Leber und Fettgewebe via Hedgehog Signalweg?
A3_38
Jahn, D; Fleet, JC; Kraus, D; Schmitt, J; Hermanns, HM; Geier, A: Vitamin D Receptor Modulates Intestinal Lipid Metabolism, Adipose Tissue Inflammation and Hepatic Steatosis in Diet-induced Obese Mice
A3_39
Bonus, M; Sommerfeld, A; Häussinger, D; Gohlke, H: α5β1 Integrins are Receptors for Bile Acids with a (Nor-)Ursodeoxycholane Scaffold