DOI: 10.1055/s-00000131

Synfacts

Ausgabe 12 · Volume 16 · Dezember 2020 DOI: 10.1055/s-010-49806

Synform

  • A171

    SYNFORM ISSUE 2020/12

    • Synthesis of Natural Products and Potential Drugs

  • z1383

    All PDFs of this category

  • 1383

    Total Synthesis of (±)-Tronocarpine

  • 1384

    Synthesis of a Remdesivir Intermediate

  • 1385

    Synthesis of Olodanrigan

  • 1386

    Synthesis of (±)-Liangshanone

  • 1387

    Total Synthesis of (+)-Formosalides A and B

  • 1388

    Synthesis of Ritobegron Ethyl Hydrochloride

  • 1389

    Synthesis of MK-5204

  • 1390

    Enantioselective Synthesis of (–)-Deoxoapodine

  • 1391

    Synthesis of (–)-Flueggenines D and I

  • 1392

    Synthesis of BMS-986235/LAR-1219

  • 1393

    Asymmetric Synthesis of an hNK1 Inhibitor

  • 1394

    Synthesis of A-1331852

  • 1395

    Formal Synthesis of (–)-Quinine

  • 1396

    Total Synthesis of (+)-Jolantidine

    • Synthesis of Heterocycles

  • z1397

    All PDFs of this category

  • 1397

    Iodine/Trifluoroacetic Acid-Assisted Multicomponent Synthesis of 4(3H)-Quinazolinones

  • 1398

    Electrocatalytic Decarboxylative Synthesis of 1,3,4-Oxadiazoles

  • 1399

    Tuning Redox Properties of Bistetronates through Spacer Selection

  • 1400

    Stereoselective Synthesis of Cyclopenta[c]pyrazoles by an Interrupted Ohira–Bestmann Reaction

  • 1401

    Hypervalent Iodine(III)-Mediated Synthesis of Spirooxazolines

  • 1402

    Regioselective C–H Arylation of Quinolone Derivatives

  • 1403

    Synthesis of Oxygen-Rich Polycyclic Scaffolds

  • 1404

    [4+1]-Spiroannulation of Bromophenols with α,β-Unsaturated Imines: Synthesis of Azaspirocycles

  • 1405

    Cobalt-Catalyzed Synthesis of Pyrroles from Nitroarenes

  • 1406

    Synthesis of 1,3,4,11-Tetrahydrooxocino[3,4-b]indoles

  • 1407

    Synthesis of 1,2,3-Benzothiazaphosphole 1,1-Dioxides

  • 1408

    Diverse Syntheses of Furochromone-Based Antimicrobial Agents

  • 1409

    Asymmetric Synthesis of Spiro-Benzofurans and Fused Benzopyrans

    • Synthesis of Materials and Unnatural Products

  • z1411

    All PDFs of this category

  • 1411

    Peeling Carbon Onions

  • 1412

    Mechanochemistry at its Best! An Improved Synthesis of Corannulene-Based Nanographene

  • 1413

    Extended Porphyrins Containing One or Two Naphthalimide Subunits

  • 1414

    Dioxa[6]helicenes, Expedited

  • 1415

    Naphthalene Diimides with Fused Sulfur Heterocycles

  • 1416

    Metal-Free Synthesis of 7-Hydroxy-6H-naphtho[2,3-c]coumarins

  • 1417

    In with the Old, Out with the New: Homologation of Fischer Indolization to Synthesize Quinolines

  • 1418

    Pick Your Own (Regioselective) Addition

  • 1419

    Expanding the Library of Cationic [5]Helicenes

  • 1420

    Working the Strain Off Cyclooctadiene-Diynes to Scale-Up Cyclic Polymer Synthesis

  • 1421

    Synthesis of a Condensed Phenoxazine Dimer and Its Radical Cation Salt

  • 1422

    Unsymmetrical Diarylation of Perylene Diimides

    • Metals in Synthesis

  • z1423

    All PDFs of this category

  • 1423

    Deoxygenation and Borylation of Ketones via Rhodium Catalysis

  • 1424

    Regiodivergent Hydrofunctionalization of α,β-Unsaturated Carboxylic Acids

  • 1425

    Asymmetric Synthesis of Amino Alcohols Using a Catalytically Formed Chiral Auxiliary

  • 1426

    Direct Chlorination of Acrylamide Derivatives

  • 1427

    α-Alkylation of Unprotected Alicyclic Amines

  • 1428

    Manganese-PN3 Catalyst Generating Tetrahydro-quinolines via a Hydrogen-Borrowing Mechanism

  • 1429

    Aza-Paternò–Büchi Reaction for Synthesis of Fused Azetidines

  • 1430

    Ruthenium-Catalyzed C(sp3)–H Bond Oxygenation of N-Benzoyloxycarbamates

  • 1431

    Air-Stable Palladium(I) Dimer for Olefin Migration and C–C Coupling

  • 1432

    Ligand-Free Regioselective Iron-Catalyzed Hydroboration of Terminal Alkenes

  • 1433

    Remote Catalytic Reductive C–H Carboxylation of Arenes with CO2 via 1,4-Nickel Migration

  • 1434

    Copper-Catalyzed C–N Cross-Coupling of Sterically Hindered Aryl Halides and Amines

  • 1435

    Iron-Catalyzed Preparation of Sulfinamides from Thiols

  • 1436

    Rhodium-Catalyzed Preparation of Pyrrolidines from Primary Amines

  • 1437

    Iridium-Catalyzed Asymmetric Synthesis of 1,2-Fluorohydrins

  • 1438

    Direct and Selective Palladium-Catalyzed Carbonylation of Allylic Alcohols

  • 1439

    Accessing (Multi)Fluorinated Piperidines Using Heterogeneous Hydrogenation

  • 1440

    Enantioselective [4+1] Cycloaddition by a Dinuclear Nickel Catalyst

  • 1441

    Nickel-Catalyzed Enantioselective Migratory Hydrocyanation of Nonconjugated Dienes

  • 1442

    Enantioconvergent Coupling of Racemic Alkyl Bromides with Azole C–H Bonds

  • 1443

    Titanium-Catalyzed Deoxygenative Radical C−C Bond-Forming Reaction of Tertiary Alcohols

  • 1444

    Palladium-Catalyzed Synthesis of Coumarins with β-Borylacrylates

  • 1445

    Migratory Cross-Coupling of Alkyl Halides via Nickel Catalysis

  • 1446

    α-C–H Alkynylation of N‑Alkylamines by Copper/Lewis Acid Catalysis

  • 1447

    para-Selective Arylation via Norbornene Relay Palladation

  • 1448

    Electrophotocatalytic Azidation of C(sp3)–H Bonds

  • 1449

    Nickel-Catalyzed Defluorination of Aromatic Amides

  • 1450

    Regioselective Markovnikov Cobalt-Catalyzed Hydroboration of Alkynes

  • 1451

    Cross-Coupling of Organosilanes with Organic Halides Mediated by Palladium Catalyst and TASF

    • Polymer-Supported Synthesis

  • z1453

    All PDFs of this category

  • 1453

    One-Pot Two-Step Catalytic Asymmetric Michael Addition/Hydrogenation

  • 1454

    Photocatalytic Pinacol Coupling of Benzaldehydes Using ZnIn2S4 Nanosheets

  • 1455

    Heterogeneous Ruthenium/Tungsten-Catalyzed One-Pot Reductive Amination of Carboxylic Acids

  • 1456

    Indenoquinoxalines Synthesis on Chitosan-Modified MnFe2O4 Magnetic Nanoparticles

  • 1457

    Hydrogenation of N-Hetarenes on Silica-Supported Cobalt/Carboxylic Acid Nanoparticles

  • 1458

    Synthesis of Benzimidazoles and Benzothiazoles on Pt NPs Supported on a Sulfur-Containing Dendrimer

  • 1459

    Decarboxylative Alkynylation of Carboxylic Acid Promoted by Graphitic Carbon Nitride

  • 1460

    Ruthenium/Magnesium Oxide-Catalyzed Direct Amination of Alcohols with Ammonia

  • 1461

    Gold-Catalyzed Carboxylation and Hydration of Terminal Aralkynes

  • 1462

    Aromatic Hydrogenation under Ambient Conditions

    • Organo- and Biocatalysis

  • z1463

    All PDFs of this category

  • 1463

    A Selenium-Catalyzed Oxidative Allylic Sulfonamidation

  • 1464

    Organic Photocatalyzed Radical–Radical Cross-Coupling toward Heteroarylamines

  • 1465

    Organophotoredox-Catalyzed Reductive Cleavage of Oxidized Lignin Model Substrates

  • 1466

    Enantioselective Acylation of 3-Hydroxyphthalides by Pyrrolomidazole-Catalyzed Dynamic Kinetic Resolution

  • 1467

    Radical-Cation-Accelerated Nucleophilic Aromatic Substitution of Electron-Rich Aryl Fluorides

  • 1468

    Tandem Catalytic Dynamic Kinetic Resolutions toward Two-Axis Atropisomers

  • 1469

    Ene-Reductase Permits Asymmetric Reductive Cyclization via Photoenzymatic Generation of Radicals

  • 1470

    Chiral Confinement Permits Enantiocontrolled Reactions To Proceed via Nonclassical Carbocations

  • 1471

    P(III)/P(V)-Catalyzed Reductive Methylamination of Arylboronic Acids and Esters with Nitromethane

  • 1472

    Asymmetric 1,4-Reduction of 2-Vinylazaarenes with Pinacolborane

  • 1473

    Carbocationic Rearrangements: Aryl-Iodide-Catalyzed Enantioselective Synthesis of 1,3-Difluorides

    • Chemistry in Medicine and Biology

  • z1475

    All PDFs of this category

  • 1475

    Next Generation Vancomycin Total Synthesis

  • 1476

    Introducing a Chiral Tricycle that Renders a Selective JAK Inhibitor

  • 1477

    Overcoming Vat Resistance with de Novo Synthesis of New Group A Streptogramin Analogues

  • 1478

    Radical Difluorination

  • 1479

    Local Labeling of Lipids

  • 1480

    Diversity-Oriented Synthesis of Acylphloroglucinol Scaffolds

  • 1481

    First Simultaneous Removal of SIRT2 Deacetylase and Defatty-Acylase Activities with PROTACs

  • 1482

    A New Generation of Molecular Imaging Probes for Carbon Monoxide Detection in Living Systems

  • 1483

    Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ)

  • 1484

    Stereoselective Covalent Inhibitors of T-Cell Activation

  • 1485

    Progesterone from Mexican Yams

  • 1486

    Sulfuramidimidoyl Fluorides as SuFEx Electrophiles for the Inverse Drug Discovery of Covalent Drugs

    • Peptide Chemistry

  • z1487

    All PDFs of this category

  • 1487

    Visible-Light-Mediated Functionalization of Cysteine Derivatives and Cysteine-Containing Peptides

  • 1488

    Synthesis of Hexahydropyrrolo[3,4-b]pyrrole-Fused Quinolines from α-Amino Acid Methyl Esters

  • 1489

    Iridium-Catalyzed Synthesis of Quaternary α- through ε-Amino Acid Derivatives

  • 1490

    Palladium-Catalyzed Synthesis of Azatryptophan Analogues

  • 1491

    Copper-Catalyzed Synthesis of Peptide-Containing Macrocyclic Alkynyl Sulfides

  • 1492

    Photoredox-Catalyzed Synthesis of γ-Amino Acids from Styrenes, Amines, and CO2

  • 1493

    Three-Component Reaction Toward γ-Carbonyl-α-Amino Acids

  • 1494

    Modification of the N-Terminus of Peptides

  • 1495

    Synthesis of Reactive Amino Acid Esters by Using Amino Acid Chlorides in a Biphasic System

    • Flow Chemistry

  • z1497

    All PDFs of this category

  • 1497

    Rhodium-Catalyzed Hydrogenation of Enamides and α-or β-Dehydroamino Acids

  • 1498

    Asymmetric Conjugate Addition–Oxidation Sequence in Flow Generating GABA Analogues

  • 1499

    Preparation and Use of Halomethyl Grignard Reagents in Continuous Flow

  • 1500

    Progress toward Fully Automated Chemical Synthesis