Am J Perinatol 2016; 33(10): 1008-1016
DOI: 10.1055/s-0036-1582129
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Center Variation in the Delivery of Indicated Late Preterm Births

Sofia Aliaga
1   Department of Pediatrics, The University of North Carolina, Chapel Hill, North Carolina
,
Jun Zhang
2   MOE-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Minhang District, Shanghai, China
,
D. Leann Long
3   Department of Biostatistics, West Virginia University, Morgantown, West Virginia
,
Amy H. Herring
3   Department of Biostatistics, West Virginia University, Morgantown, West Virginia
4   Carolina Population Center, Chapel Hill, North Carolina
,
Matthew Laughon
1   Department of Pediatrics, The University of North Carolina, Chapel Hill, North Carolina
,
Kim Boggess
5   Department of Obstetrics and Gynecology, The University of North Carolina, Chapel Hill, North Carolina
,
Uma M. Reddy
6   Pregnancy and Perinatology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
,
Katherine Laughon Grantz
7   Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
› Author Affiliations
Further Information

Publication History

28 May 2015

24 February 2016

Publication Date:
27 April 2016 (online)

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Abstract

Objective Evidence for optimal timing of delivery for some pregnancy complications at late preterm gestation is limited. The purpose of this study was to identify center variation of indicated late preterm births.

Study design We performed an analysis of singleton late preterm and term births from a large U.S. retrospective obstetrical cohort. Births associated with spontaneous preterm labor, major congenital anomalies, chorioamnionitis, and emergency cesarean were excluded. We used modified Poisson fixed effects logistic regression with interaction terms to assess center variation of indicated late preterm births associated with four medical/obstetric comorbidities after adjusting for socio-demographics, comorbidities, and hospital/provider characteristics.

Results We identified 150,055 births from 16 hospitals; 9,218 were indicated late preterm births. We found wide variation of indicated late preterm births across hospitals. The extent of center variation was greater for births associated with preterm premature rupture of membranes (risk ratio [RR] across sites: 0.45–3.05), hypertensive disorders of pregnancy (RR across sites: 0.36–1.27), and placenta previa/abruption (RR across sites: 0.48–1.82). We found less center variation for births associated with diabetes (RR across sites: 0.65–1.39).

Conclusion Practice variation in the management of indicated late preterm deliveries might be a source of preventable late preterm birth.