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Digestive Disease Interventions 2024; 08(01): 82-91
DOI: 10.1055/s-0043-1772164
Review Article

Transarterial Radioembolization for Hepatic Malignancies in North and South America

Willian Yoshinori Kawakami 
1   Department of Interventional Radiology, Radiology Institute, University of Sao Paulo Medical School, São Paulo/SP, Brazil
,
Andre Moreira de Assis 
1   Department of Interventional Radiology, Radiology Institute, University of Sao Paulo Medical School, São Paulo/SP, Brazil
,
Emil Israel Cohen 
2   Department of Radiology, MedStar Georgetown University Hospital, Washington, District of Columbia
,
Nathan Elie Frenk 
2   Department of Radiology, MedStar Georgetown University Hospital, Washington, District of Columbia
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Abstract

Transarterial radioembolization (TARE) with yttrium 90 is increasingly utilized for the treatment of hepatic neoplasms, whether primary (particularly hepatocellular carcinoma [HCC]) or metastatic (particularly colorectal). Extensive data and practical experience have led to a better understanding of its most appropriate usage and optimal techniques, particularly regarding dosimetry. Different clinical contexts and technical parameters allow its use with either palliative or curative intent. Improved patient outcomes have led to its inclusion in management guidelines of HCC and colorectal cancer. While available in multiple centers in the United States and Canada, its availability in South America is still very limited. The objective of this article is to review available treatment platforms, indications, techniques, recent advances, and clinical results, as well as briefly explore the disparities in availability throughout the United States.

Keywords

transarterial radioembolization - hepatocellular carcinoma - liver metastases - yttrium 90


Publication History

Received: 08 December 2022

Accepted: 05 July 2023

Article published online:
03 August 2023

© 2023. Thieme. All rights reserved.

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