Synthesis of Dibenzo[f,h]quinolines by Stepwise C–H Arylation of 2-Phenylpyridine and Reductive Cyclodehydrogenation

Dedicated to Prof. Guo-Qiang Lin on the occasion of his 80^th birthday.

Abstract

A synthetic approach to dibenzo[f,h]quinolines and their derivatives via stepwise ruthenium-catalyzed C–H arylation and potassium-mediated reductive cyclodehydrogenation from 2-phenylpyridine and aryl bromides, is presented. One dibenzo[f,h]quinoline derivative is used as a bidentate ligand to prepare a cyclometalated ruthenium complex. Two dibenzo[f,h]quinoline compounds and the ruthenium complex were characterized by single-crystal X-ray structural analysis.

Key words

dibenzo[f,h]quinolones - polycyclic aromatic hydrocarbons - C–H arylation - reductive cyclodehydrogenation - ruthenium

Publikationsverlauf

Eingereicht: 26. Februar 2023

Angenommen nach Revision: 05. April 2023

Accepted Manuscript online:
05. April 2023

Artikel online veröffentlicht:
08. Mai 2023

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