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Synthesis 1985; 1985(11): 1052-1055
DOI: 10.1055/s-1985-31425
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Asymmetric Syntheses via Heterocyclic Intermediates; XXVII1. Enantioselective Synthesis of [2-Methoxyethoxymethyl-Protected] (R)- Homoserine Methyl Esters and (R)-α-Methyl-homoserine Methyl Esters and of the Corresponding α-Amino-γ-lactones by the Bis-lactim Ether Method

Reinhold Gull* , Ulrich Schöllkopf
  • *Institut für Organische Chemie der Universität Göttingen, Tammannstraße 2, D-3400 Göttingen, Federal Republic of Germany
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Publication Date:
27 September 2002 (online)

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An asymmetric synthesis of various (R)-homoserine methyl esters and (R)-α-methylhomoserine methyl esters starting from the bis-lactim ethers of cyclo-(L-Val-Gly) and cyclo-(L- Val-Ala) and oxiranes is described.