Planta Med 2018; 84(09/10): 627-637
DOI: 10.1055/a-0585-6153
Reviews
Georg Thieme Verlag KG Stuttgart · New York

A Review of the Traditional Uses, Phytochemistry and Biological Activities of the Genus Santolina

Rosa Tundis
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Italy
,
Monica Rosa Loizzo
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Italy
› Author Affiliations
Further Information

Publication History

received 15 November 2017
revised 05 February 2018

accepted 16 February 2018

Publication Date:
08 March 2018 (online)

Abstract

The genus Santolina is a taxonomically complex group of plant species widely distributed in the Mediterranean flora and used in traditional medicine since ancient times for their biological properties, including antimicrobial, anti-inflammatory, antispasmodic, digestive, and analgesic activities. Phytochemical investigations of Santolina species have revealed the presence of terpenoids as the main bioactive constituents of the genus. Coumarins and flavonoids were also identified. This review deals, for the first time, with information on the traditional uses, chemical profile, and biological properties of plants of the genus Santolina in order to provide input for future research prospects.

 
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